Transcription Factor

Accessions: BARHL1 (HT-SELEX2 May2017)
Names: BARHL1, ENSG00000125492
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: Homeodomain experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: Homeodomain experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3
Length: 114
Pfam Domains: 30-86 Homeobox domain
Sequence:
(in bold interface residues)
1 SDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRM 60
61 ELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFY
Interface Residues: 30, 31, 32, 33, 71, 72, 74, 75, 78, 79, 82, 83, 86, 105
3D-footprint Homologues: 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1fjl_B, 5zfz_A, 1ig7_A, 2lkx_A, 1nk2_P, 1zq3_P, 6m3d_C, 7q3o_C, 6es3_K, 2ld5_A, 3a01_E, 7psx_B, 5hod_A, 3lnq_A, 1jgg_B, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1au7_A, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 3l1p_A, 5zjt_E, 4j19_B, 1e3o_C, 7xrc_C, 2xsd_C, 1le8_A, 1le8_B, 1du0_A, 4qtr_D, 1mnm_C, 1puf_B, 1k61_B, 1o4x_A, 8g87_X
Binding Motifs: BARHL1_2 sTAAwYGg
BARHL1_3 sTAAwyGs
BARHL1_methyl_1 sTAAttGs
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.