Transcription Factor

Accessions: Q6FHY5 (JASPAR 2024)
Names: Q6FHY5_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q6FHY5
Length: 303
Pfam Domains: 187-243 Homeobox domain
Sequence:
(in bold interface residues)
1 MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMF 60
61 ASQHHRGHHHHHHHHHHHHHQQQHQALQTNWHLPQMSSPPSAARHSLCLQPDSGGPPELG 120
121 SSPPVLCSNSSSLGSSTPTGAACAPGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYKS 180
181 EVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMK 240
241 WKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTGDSIANEDSHDSDHSSEH 300
301 AHL
Interface Residues: 187, 188, 189, 190, 228, 229, 231, 232, 235, 236, 239, 240, 243
3D-footprint Homologues: 5zfz_A, 1fjl_B, 2h1k_B, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 1mnm_C, 3d1n_M, 1nk2_P, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 2ld5_A, 7q3o_C, 6es3_K, 2hos_A, 4cyc_A, 5flv_I, 5zjt_E, 4j19_B, 3a01_E, 7psx_B, 1b72_A, 5hod_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 7xrc_C, 1e3o_C, 2xsd_C, 1au7_A, 1le8_A, 1k61_B, 3l1p_A, 1o4x_A, 8g87_X, 4qtr_D, 1du0_A
Binding Motifs: MA0706.1 rsTaATtAwc
MA0706.2 sTaATtA
Publications: Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.