Transcription Factor
| Accessions: | P70217 (JASPAR 2024) |
| Names: | Homeobox protein Hox-4.8, Homeobox protein Hox-D13, HXD13_MOUSE |
| Organisms: | Rattus norvegicus, Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P70217 |
| Length: | 339 |
| Pfam Domains: | 81-171 Hox protein A13 N terminal 273-329 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSRSGTWDMDGLRADGGAAGAAPASSSSSVAAPGQCRGFLSAPVFAGTHSGRAAAAAAAA 60 61 AAAAAAASSFAYPGTSERTGSSSSSSSSAVIATRPEAPVAKECPAPAAAATAAAPPGAPA 120 121 LGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPTNEVP 180 181 ARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYC 240 241 AKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKD 300 301 KRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS |
| Interface Residues: | 272, 273, 274, 275, 276, 314, 315, 317, 318, 321, 322, 325, 326, 329 |
| 3D-footprint Homologues: | 3a01_E, 1ig7_A, 3cmy_A, 6a8r_A, 5zfz_A, 1fjl_B, 2h1k_B, 1puf_A, 1jgg_B, 3lnq_A, 1nk2_P, 1zq3_P, 6m3d_C, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 7psx_B, 5hod_A, 2hdd_A, 2r5y_A, 1puf_B, 5jlw_D, 2hos_A, 4xrs_G, 3rkq_B, 5flv_I, 1b72_A, 5zjt_E, 4cyc_A, 1e3o_C, 2xsd_C, 7xrc_C, 1au7_A, 1le8_A, 1mnm_C, 1du0_A, 4qtr_D, 1k61_B, 1o4x_A |
| Binding Motifs: | PH0078.1 mwwyyAATAAAAhymh MA0909.3 asCAATAAAa MA0909.4 CAATAAA |
| Binding Sites: | MA0909.3.1 MA0909.3.10 MA0909.3.11 / MA0909.3.3 / MA0909.3.5 MA0909.3.12 / MA0909.3.16 / MA0909.3.18 MA0909.3.13 MA0909.3.14 MA0909.3.15 / MA0909.3.7 MA0909.3.17 MA0909.3.19 MA0909.3.2 MA0909.3.20 / MA0909.3.4 MA0909.3.6 / MA0909.3.8 MA0909.3.9 MA0909.4.1 / MA0909.4.10 / MA0909.4.11 / MA0909.4.12 / MA0909.4.13 / MA0909.4.14 / MA0909.4.15 / MA0909.4.16 / MA0909.4.17 / MA0909.4.18 / MA0909.4.20 / MA0909.4.3 / MA0909.4.4 / MA0909.4.5 / MA0909.4.6 / MA0909.4.7 / MA0909.4.8 MA0909.4.19 MA0909.4.2 MA0909.4.9 |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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