Transcription Factor

						

			
Accessions: A8WL06 (JASPAR 2024)

			
Names: Homeobox protein unc-62, UNC62_CAEBR, Uncoordinated protein 62
Organisms: Caenorhabditis briggsae
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: A8WL06
Length: 725
Pfam Domains:   570-609 Homeobox KN domain
  571-609 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MSADSKVWAHASADTWTTAQGISTYDLDTSSIKREKIDCHEQFNDGYGPPPGTASTDAVS   60
  61 YAADPTAYFNLYTNMGAAPTTTPMMHHEMGEAMKRDKEAIYAHPLYPLLVVLFEKCELAT  120
 121 STPRETSRDGTTSSDVCSSASFKDDLNEFVKHTQENADKQYYQPNPQLDQIMLQSIQMLR  180
 181 FHLLELEKVHELCDNFCNRYVTCLKGKMPLDIVGDERASSSQPPMSPGSMGHHGHSGSPS  240
 241 MGGAGAATPMHYPPPYEPQSVPLPENVLGGGHPLEMFPGSSMAYAMAGMAAAAASSSSSQ  300
 301 PQPGDHPLANGGTLHSTAGASQTLLPIAVSSPSTCSSGGLRQDSTPLSGETPMANGNSMD  360
 361 SISEAERIRRRFYMCVIVSAGPSSSSLHQHHLHHPHHFPHHQLQPPAHHQDFLLPPPPQN  420
 421 IIEQSLHCAGVSMLDASLIPPSSSSSASEYHGDMMSHMYSHHDVYHHQDMTYTDYGDYGT  480
 481 PDVVMMSSSDVKMEDAASVSSSKSGGKKQQPGTPNGRVGKSRGRDEFSVCGSNEDGRDSV  540
 541 LSDSANGSQNGKRKVPKVFSKEAITKFRAWLFQNLAHPYPSEEQKKQLAKETGLTILQVN  600
 601 NWFINARRRIVQPMIDQNNRAGRTPHMNVCKNRRRNRSEQSPGPSPDSESDSGANYSPDP  660
 661 TSLAAATAMHYPGAELYMQRTMNYGGFQPFPNPAMQFMNPMMGFPVAPAVDAISQQWIDL  720
 721 SAPHE
Interface Residues: 534, 535, 538, 551, 552, 553, 555, 556, 600, 601, 604, 605, 606, 608, 609
3D-footprint Homologues: 5zfz_A, 2lkx_A, 3d1n_M, 1au7_A, 3cmy_A, 6fqp_B, 3rkq_B, 1puf_B, 1le8_A, 4j19_B, 7q3o_C, 5hod_A, 6fqq_E, 2d5v_B, 3l1p_A, 1le8_B, 4xrm_B, 1fjl_B, 6a8r_A, 3lnq_A, 1mnm_C, 4xrs_G, 1k61_B
Binding Motifs: MA0918.1 gAsmTGTCAytt
MA0918.2 AsmTGTCA
			
Publications: Van Nostrand EL, Sánchez-Blanco A, Wu B, Nguyen A, Kim SK. Roles of the developmental regulator unc-62/Homothorax in limiting longevity in Caenorhabditis elegans. PLoS Genet : (2013;9(2):e1003325.). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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