Transcription Factor
Accessions: | FOXO4_HUMAN (HOCOMOCO 10), P98177 (JASPAR 2024) |
Names: | Fork head domain transcription factor AFX1, Forkhead box protein O4, FOXO4_HUMAN |
Organisms: | Homo sapiens |
Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | P98177 |
Length: | 505 |
Pfam Domains: | 104-185 Fork head domain |
Sequence: (in bold interface residues) | 1 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT 60 61 EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK 120 121 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML 180 181 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG 240 241 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL 300 301 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF 360 361 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE 420 421 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE 480 481 CDMDNIISDLMDEGEGLDFNFEPDP |
Interface Residues: | 146, 149, 151, 152, 153, 155, 156, 157, 159, 160, 169, 174, 193, 347 |
3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 7yzg_A, 7tdw_A, 7yz7_A, 6nce_A, 2uzk_A, 7tdx_A, 2a07_J, 7yzb_A, 3co6_C, 7vou_C, 6ako_C, 2c6y_A, 7yze_A, 7cby_C, 3g73_A, 6el8_A, 3qrf_G, 6w64_A |
Binding Motifs: | MA0848.1 GTAAACA FOXO4_HUMAN.H10MO.C|M01164 TTGTTTWyk |
Publications: | Furuyama T., Nakazawa T., Nakano I., Mori N. Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochem. J. 349:629-634 (2000). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.