Transcription Factor
| Accessions: | P46601 (JASPAR 2024), T21724 (AthalianaCistrome v4_May2016) |
| Names: | HAT2_ARATH, HD-ZIP protein 2, Homeobox-leucine zipper protein HAT2, Homeodomain-leucine zipper protein HAT2, AT5G47370, HAT2, T21724; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | JASPAR 2024 1, AthalianaCistrome v4_May2016 2 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:Homeobox |
| Length: | 283 |
| Pfam Domains: | 1-91 HD-ZIP protein N terminus 129-183 Homeobox domain 185-228 Homeobox associated leucine zipper |
| Sequence: (in bold interface residues) | 1 MMMGKEDLGLSLSLGFSQNHNPLQMNLNPNSSLSNNLQRLPWNQTFDPTSDLRKIDVNSF 60 61 PSTVNCEEDTGVSSPNSTISSTISGKRSEREGISGTGVGSGDDHDEITPDRGYSRGTSDE 120 121 EEDGGETSRKKLRLSKDQSAFLEETFKEHNTLNPKQKLALAKKLNLTARQVEVWFQNRRA 180 181 RTKLKQTEVDCEYLKRCVEKLTEENRRLQKEAMELRTLKLSPQFYGQMTPPTTLIMCPSC 240 241 ERVGGPSSSNHHHNHRPVSINPWVACAGQVAHGLNFEALRPRS |
| Interface Residues: | 107, 110, 111, 114, 127, 128, 129, 130, 131, 133, 134, 167, 168, 169, 170, 172, 173, 176, 177, 180, 181, 183, 184 |
| 3D-footprint Homologues: | 5zfz_A, 7z5k_B, 1puf_A, 1zq3_P, 3lnq_A, 2lkx_A, 2ld5_A, 2r5y_A, 7psx_B, 6a8r_A, 3a01_E, 3cmy_A, 2h1k_B, 1puf_B, 1fjl_B, 5flv_I, 3d1n_M, 1nk2_P, 3rkq_B, 2glo_A, 5jlw_D, 1ig7_A, 7q3o_C, 1e3o_C, 1le8_A, 7xrc_C, 1au7_A, 1b72_A, 5zjt_E, 4qtr_D, 5hod_A, 1o4x_A, 1du0_A, 4xrm_B, 1jgg_B, 6es3_K, 4xrs_G, 4cyc_A, 2hdd_A, 2hos_A, 6m3d_C |
| Binding Motifs: | M0428 / MA1198.1 wyyAATCATtw M0432 yyAATCATTwa MA1198.2 yAATCATt |
| Publications: | Sessa G., Morelli G., Ruberti I. The Athb-1 and -2 HD-Zip domains homodimerize forming complexes of different DNA binding specificities. EMBO J. 12:3507-3517 (1993). [Pubmed] |
| Related annotations: | PaperBLAST |
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