Transcription Factor
| Accessions: | HXA10_MOUSE (HOCOMOCO 10), P31310 (JASPAR 2024) |
| Names: | Homeobox protein Hox-1.8, Homeobox protein Hox-A10, HXA10_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P31310 |
| Length: | 416 |
| Pfam Domains: | 343-399 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSARKGYLLPSPNYPTTMSCSESPAANSFLVDSLISSGRGEAGVGGGSAGGGGGGYYAHG 60 61 GVYLPPASDLPYGLQSCGLFPALGSKRNEAPSPGGGGGGGSGGLGPGTHGYAPAPLDLWL 120 121 DAPRSCRMEPPDGPPPPQPQPQQQQQQPPPPPPQPPQPQPQATSCSFAQNIKEESSYCLY 180 181 DAADKCPKGSAAADLAPFPRGPPPDGCALGASSGVPVPGYFRLSQAYGTAKGFGSGGGGT 240 241 QQLASPFPAQPPGRGFDPPPALASGSTEAAGKERVLDSTPPPTLVCTGGGGSQGDEEAHA 300 301 SSSAAEELSPAPSENSKASPEKDSLGSSKGENAANWLTAKSGRKKRCPYTKHQTLELEKE 360 361 FLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS |
| Interface Residues: | 343, 344, 345, 346, 384, 385, 387, 388, 391, 392, 395, 396, 399 |
| 3D-footprint Homologues: | 6a8r_A, 6m3d_C, 1fjl_B, 2h1k_B, 5zfz_A, 1puf_A, 1ig7_A, 3cmy_A, 1jgg_B, 1nk2_P, 1zq3_P, 3lnq_A, 2lkx_A, 2ld5_A, 6es3_K, 7q3o_C, 1puf_B, 5hod_A, 2hos_A, 1au7_A, 5jlw_D, 4xrs_G, 3a01_E, 7psx_B, 1b72_A, 3rkq_B, 5flv_I, 2hdd_A, 5zjt_E, 4cyc_A, 2r5y_A, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 6fqq_E, 3d1n_M, 4qtr_D, 1k61_B, 1o4x_A, 6fqp_B, 1mnm_C, 1du0_A |
| Binding Motifs: | HXA10_MOUSE.H10MO.C|M01153 kayrrTTTATGw PH0046.1 dmgGyMATWAAAtkmw |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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