Transcription Factor
Accessions: | ZIC1_HUMAN (HOCOMOCO 10), Q15915 (JASPAR 2024) |
Names: | ZIC1_HUMAN, Zinc finger protein 201, Zinc finger protein of the cerebellum 1, Zinc finger protein ZIC 1 |
Organisms: | Homo sapiens |
Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | Q15915 |
Length: | 447 |
Pfam Domains: | 242-260 C2H2-type zinc finger 275-296 C2H2-type zinc finger 289-314 Zinc-finger double domain 302-326 C2H2-type zinc finger 302-326 Zinc finger, C2H2 type 318-345 Zinc-finger double domain 332-356 C2H2-type zinc finger 350-373 Zinc-finger double domain 362-384 Zinc finger, C2H2 type 362-384 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 MLLDAGPQYPAIGVTTFGASRHHSAGDVAERDVGLGINPFADGMGAFKLNPSSHELASAG 60 61 QTAFTSQAPGYAAAAALGHHHHPGHVGSYSSAAFNSTRDFLFRNRGFGDAAAAASAQHSL 120 121 FAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASPNVVNGQMRLGFSGDMYPRPEQYGQ 180 181 VTSPRSEHYAAPQLHGYGPMNVNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKK 240 241 SCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEK 300 301 PFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDK 360 361 PYLCKMCDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTS 420 421 SLSPSSSAVHHTAGHSALSSNFNEWYV |
Interface Residues: | 247, 248, 250, 251, 254, 284, 285, 286, 287, 288, 290, 291, 295, 302, 314, 315, 316, 317, 318, 320, 321, 322, 323, 324, 326, 327, 330, 339, 344, 345, 346, 347, 348, 349, 350, 351, 352, 355, 372, 373, 374, 375, 376, 377, 378, 379, 380, 403, 404 |
3D-footprint Homologues: | 5v3j_F, 1ubd_C, 7w1m_H, 8cuc_F, 1tf3_A, 7n5w_A, 8ssq_A, 6ml4_A, 4x9j_A, 5kkq_D, 8ssu_A, 5ei9_F, 8gn3_A, 2gli_A, 1tf6_A, 7eyi_G, 2i13_A, 7ysf_A, 6wmi_A, 6e94_A, 5k5i_A, 5und_A, 2lt7_A, 2kmk_A, 7y3l_A, 3uk3_C, 6jnm_A, 1llm_D, 2v6e_B, 1mey_C, 6blw_A, 5yel_A, 5kl3_A, 1g2f_F, 6u9q_A, 8h9h_G, 7y3m_I, 6a57_A, 2jpa_A, 6sjf_B, 5k5l_F, 2wbs_A, 2drp_D, 1f2i_J, 5yj3_D, 7txc_E, 4m9v_C |
Binding Motifs: | MA0696.1 gACCCCCyGCTGyG ZIC1_HUMAN.H10MO.B|M01616 kGGGwGGks |
Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.