Transcription Factor
Accessions: | T049021_1.02 (CISBP 1.02), O88282 (JASPAR 2024) |
Names: | Bcl6b, T049021_1.02;, B-cell CLL/lymphoma 6 member B protein, Bcl6-associated zinc finger protein, BCL6B_MOUSE |
Organisms: | Mus musculus |
Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | experiment type:PBM, family:C2H2 ZF |
Length: | 474 |
Pfam Domains: | 28-134 BTB/POZ domain 323-345 Zinc finger, C2H2 type 323-345 C2H2-type zinc finger 337-361 Zinc-finger double domain 351-369 Zinc-finger of C2H2 type 351-373 Zinc finger, C2H2 type 351-371 C2H2-type zinc finger 365-389 Zinc-finger double domain 379-401 Zinc finger, C2H2 type 379-401 C2H2-type zinc finger 393-418 Zinc-finger double domain 407-429 C2H2-type zinc finger 407-429 Zinc finger, C2H2 type 422-445 Zinc-finger double domain |
Sequence: (in bold interface residues) | 1 MGSTAAPEGALGYVREFTRHSSDVLSNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACS 60 61 GFFYSIFRGRAGLGVDVLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQM 120 121 EHVVQACHRFIQASYEPLGISLRPVEVEPPRPPTVAPPGSPRRSEGHPDPPTESRSCSQG 180 181 SPSPASPDPKACNWKKYKFIVLNSQTSQAGSLVGESSGQPCPQARLPSGDEACSSSSSSE 240 241 EGTTPGLQSRLSLATTTARFKCGALANNSYLFTPRAQETSLPASKQANPPPGSEFFSCQN 300 301 CEAVAGCSSGLELLAPGDEDKPYKCQLCRSAFRYKGNLASHRTVHTGEKPYRCSICGARF 360 361 NRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQ 420 421 TLKSHVRIHTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGAATNTKVRYHILGGP |
Interface Residues: | 307, 309, 310, 313, 333, 334, 335, 336, 337, 339, 340, 342, 343, 344, 346, 351, 361, 362, 363, 364, 365, 367, 368, 372, 389, 390, 391, 392, 393, 395, 396, 397, 417, 418, 419, 420, 421, 422, 423, 424, 425, 427, 446, 447, 448, 449, 450, 451, 452 |
3D-footprint Homologues: | 7w1m_H, 5v3j_F, 7y3l_A, 7n5w_A, 5kkq_D, 6wmi_A, 8ssq_A, 5und_A, 2gli_A, 8ssu_A, 6ml4_A, 8gn3_A, 8h9h_G, 7eyi_G, 7y3m_I, 7ysf_A, 2i13_A, 5yel_A, 2jpa_A, 1ubd_C, 2kmk_A, 1tf3_A, 6jnm_A, 8cuc_F, 6blw_A, 6u9q_A, 5ei9_F, 1mey_C, 5kl3_A, 1f2i_J, 5k5i_A, 1g2f_F, 1tf6_A, 4x9j_A, 1llm_D, 6e94_A, 2lt7_A, 7txc_E, 2drp_D, 5yj3_D, 4m9v_C, 6a57_A, 3uk3_C, 2wbs_A, 5k5l_F |
Binding Motifs: | PB0006.1 wcTTTCkAGGAAttys PB0110.1 hbscCCgCCCCwhmwm M0391_1.02 tyctrGRAarrm |
Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.