Transcription Factor
| Accessions: | T061538_1.02 (CISBP 1.02), Q12041 (JASPAR 2024) |
| Names: | MET32, T061538_1.02;, MET32_YEAST, Methionine-requiring protein 32, Transcriptional regulator MET32 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:C2H2 ZF |
| Length: | 191 |
| Pfam Domains: | 98-120 Zinc finger, C2H2 type 98-120 C2H2-type zinc finger 127-147 C2H2-type zinc finger 128-146 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MEDQDAAFIKQATEAIVDVSLNIDNIDPIIKELLERVRNRQNRLQNKKPALIPAENGVDI 60 61 NSQGGNIKVKKENALPKPPKSSKSKPQDRRNSTGEKRFKCAKCSLEFSRSSDLRRHEKTH 120 121 FAILPNICPQCGKGFARKDALKRHYDTLTCRRNRTKLLTAGGEGINELLKKVKQSNIVHR 180 181 QDNNHNGSSNG |
| Interface Residues: | 87, 91, 98, 108, 109, 110, 111, 112, 114, 115, 116, 118, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 147 |
| 3D-footprint Homologues: | 8h9h_G, 7n5w_A, 7w1m_H, 2kmk_A, 1tf3_A, 1g2f_F, 8cuc_F, 5ei9_F, 7y3l_A, 2drp_D, 1f2i_J, 5kkq_D, 6wmi_A, 5yel_A, 4x9j_A, 8ssq_A, 6e94_A, 5kl3_A, 2wbs_A, 1tf6_A, 5yj3_D, 2i13_A, 1llm_D, 6ml4_A, 5und_A, 3uk3_C, 1ubd_C, 8gn3_A, 6blw_A, 5k5i_A, 2jpa_A, 1mey_C, 6u9q_A, 2gli_A, 5v3j_F, 4m9v_C, 7ysf_A, 7eyi_G, 7y3m_I, 7txc_E, 6dnw_A |
| Binding Motifs: | M0509_1.02 sTGTGGCkyc MA0334.1 mGCCACa MA0334.2 GCCACa |
| Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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