Transcription Factor

						

			
Accessions: 5nj8_A (3D-footprint 20231221)

			
Names: Ah receptor, AHR_HUMAN, Aryl hydrocarbon receptor, bHLHe76, Class E basic helix-loop-helix protein 76
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P35869
Length: 176
Pfam Domains:      4-45 Helix-loop-helix DNA-binding domain
   61-123 PAS fold
Sequence: 
(in bold interface residues)		   1 NPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKGLNLQ   60
  61 EGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQ  120
 121 LHWPPENSPLMERCFICRLRCLLDSSGFLAMNFQGKLKYLHGQKPQLALFAIATPL
Interface Residues: 3, 6, 7, 33, 90
3D-footprint Homologues: 5gnj_I, 7xhv_B, 7d8t_A, 5nj8_C, 7f2f_B, 7xi3_B, 6g1l_A, 5sy7_B, 1am9_A, 5v0l_A, 4h10_A, 7xi3_A, 4h10_B, 5nj8_D, 4zpk_A, 7ssa_L, 5v0l_B, 1a0a_B, 6rar_I
Binding Motifs: 5nj8_AB TtgCGTGA
			
Publications: Schulte KW, Green E, Wilz A, Platten M, Daumke O. Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation. Structure 25:1025-1033 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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