Transcription Factor
| Accessions: | Q32NY8 (JASPAR 2024) |
| Names: | Q32NY8_MOUSE, Tcfl5 protein, Transcription factor-like 5 (basic helix-loop-helix |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q32NY8 |
| Length: | 489 |
| Pfam Domains: | 390-440 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MSGPGPREPPPEAGATGGEAGPEGAGGGDAALGEPGLSFTTTDLSLVEMTEVEYTQLQHI 60 61 LYSHMEAADGELEARLGSALLAGPGAGSGAAGSLAPAPPVYPVLCPPLAADAPCLGHVDF 120 121 QELRMMLLGEAGAAEKTPGGADGTRTRADGVAKEGAGGAGPDGAPEARAKPTVRVRLEDR 180 181 FNSMPAEPPAPRGAEPAESGVALNNLVTLIRHPSELMNVPLHQQQNKCTTLVKNKTAAAT 240 241 TALQFTYPLFTSACSTGGNASLAQTQSSSNSCSILEAAKHQDIGLPRAFSFCYQQEIEST 300 301 KQTGGSRNKALPEQVWIKVGEALCKQAINKRNRSRIRQLDTSVERRALGEIQNVGEGSST 360 361 SQGTWQSSESSQSNLGEQTQSGPQGGRSQRRERHNRMERDRRRRIRICCDELNLLVPFCN 420 421 AETDKATTLQWTTAFLKYIQERHGDSLKKEFESVFCGKTGRRLKLTRPESLVTCPAQGSL 480 481 QSSPAMEIK |
| Interface Residues: | 391, 393, 394, 395, 397, 398, 401, 402, 406, 425, 436 |
| 3D-footprint Homologues: | 1a0a_B, 1an4_A, 4zpk_A, 6g1l_A, 7xi3_A, 5eyo_A, 4h10_A, 7xq5_A, 5nj8_D, 7d8t_A, 4h10_B, 8osl_O, 5v0l_A, 7ssa_L, 8osl_P, 2ql2_D, 6sa1_A |
| Binding Motifs: | MA0632.1 rkCrCGyGmy |
| Publications: | Siep M, Sleddens-Linkels E, Mulders S, van Eenennaam H, Wassenaar E, Van Cappellen WA, Hoogerbrugge J, Grootegoed JA, Baarends WM. Basic helix-loop-helix transcription factor Tcfl5 interacts with the Calmegin gene promoter in mouse spermatogenesis. Nucleic Acids Res 32:6425-36 (2004). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.