Transcription Factor

Accessions: sd (DrosophilaTF 1.1), P30052 (JASPAR 2024)
Names: SCAL_DROME
Organisms: Drosophila melanogaster
Libraries: DrosophilaTF 1.1 1, JASPAR 2024 2
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 440
Pfam Domains: 78-169 TEA/ATTS domain family
185-432 TEA/ATTS domain family
Sequence:
(in bold interface residues)
1 MKNITSSSTCSTGLLQLQNNLSCSELEVAEKTEQQAVGPGTIPSPWTPVNAGPPGALGSA 60
61 DTNGSMVDSKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSD 120
121 EGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKVQFWQPGLQPST 180
181 SQDFYDYSIKPFPQPPYPAGKTSTAVSGDETGIPPSQLPWEGRAIATHKFRLLEFTAFME 240
241 IQRDEIYHRHLFVQLGGKPSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLV 300
301 KCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLEN 360
361 NRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYV 420
421 FEVAAQNSGTTHHIYRLIKE
Interface Residues: 124, 128, 145, 146, 149, 150, 153, 154, 157
3D-footprint Homologues: 5gzb_A, 5no6_N
Binding Motifs: MA0243.1 gwmATTycwmrr
sd wrnATkTnT
MA0243.2 gwmATTycwmr
Binding Sites: MA0243.1.1
MA0243.1.10
MA0243.1.11
MA0243.1.12
MA0243.1.13
MA0243.1.14
MA0243.1.2
MA0243.1.3
MA0243.1.4
MA0243.1.5
MA0243.1.6
MA0243.1.7 / MA0243.1.8
MA0243.1.9
MA0243.2.1
MA0243.2.10
MA0243.2.11
MA0243.2.12
MA0243.2.13
MA0243.2.14
MA0243.2.2
MA0243.2.3
MA0243.2.4
MA0243.2.5
MA0243.2.6
MA0243.2.7 / MA0243.2.8
MA0243.2.9
Publications: Lunde Karen, Trimble Jennifer L., Guichard Annabel, Guss Kirsten A., Nauber Ulrich, Bier Ethan. Activation of the knirps locus links patterning to morphogenesis of the second wing vein in Drosophila.. Development 130:235-248 (2003). [Pubmed]

Bergman C.M, Carlson J.W, Celniker S.E. Drosophila DNase I footprint database: a systematic genome annotation of transcription factor binding sites in the fruitfly, Drosophila melanogaster. Bioinformatics (Oxford, England) 21:1747-9 (2005). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.