Transcription Factor

Accessions: UP00020A (UniPROBE 20160601)
Names: activating transcription factor 1, Atf1, Cyclic AMP-dependent transcription factor ATF-1, TCR-ATF1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P81269
Description: activating transcription factor 1: Mus musculus activating transcription factor 1 (Atf1), mRNA
Length: 76
Pfam Domains: 17-72 bZIP transcription factor
20-68 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 MTSPVTLTSQTTKTDDPQLRREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTL 60
61 IEELKTLKDLYSHKSV
Interface Residues: 24, 28, 29, 31, 32, 35, 36
3D-footprint Homologues: 4eot_A, 2wt7_B, 7x5e_F, 5t01_B, 1dh3_C, 5vpe_D
Binding Motifs: UP00020A_1 ackrTGACGTCAycra
UP00020A_2 gdaTGACGaryAwm
Binding Sites: CTACGTCA
TGACGTAA
AACGTCAT
AATGACGT
ACGTCACA
ACGTCACC
ACGTCACG
ACGTCACT
ACGTCATA
ACGTCATC
ACGTCATG
ATGACGTA
ATGACGTC
ATGACGTG
ATTACGTA
CACGTCAC
CGTCATAA
CGTCATCA
GTGACGTA
TCACGTCA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.