Transcription Factor

Accessions: P34766 (JASPAR 2024)
Names: Caudal homolog 1, Homeobox protein ceh-3, Homeobox protein pal-1, PAL1_CAEEL, Posterior alae in males protein 1
Organisms: Caenorhabditis elegans
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P34766
Length: 270
Pfam Domains: 208-263 Homeobox domain
Sequence:
(in bold interface residues)
1 MSVDVKSDFSENESSSTPSPTTVPADVTWPHYPMMPFMQPHPLREKMLQPTFDPQIYGRW 60
61 SQMGDTGFYGHPDLYPFGLPQLAANGQIPAVEAVDVKPPLSNGSSSSDSGMYPSPSDMMT 120
121 PFPSTSSGAASSSELSAAAAAAANYQMRAATCYQQSVWPFMDYQQFQGFSWKMPLGNNHG 180
181 KDRRSSSDGKTLPTGPGTNNVRVRTADKYRMVYSDYQRLELEKEFHTSPFITSDRKSQLS 240
241 TMLSLTERQIKIWFQNRRAKDRRDKQKIRL
Interface Residues: 201, 204, 207, 208, 209, 210, 213, 248, 249, 251, 252, 255, 256, 259, 260, 263
3D-footprint Homologues: 2h1k_B, 1puf_A, 2lkx_A, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 3lnq_A, 7q3o_C, 6es3_K, 2ld5_A, 5jlw_D, 3rkq_B, 4xrs_G, 3cmy_A, 2hdd_A, 5zfz_A, 4cyc_A, 2r5y_A, 5flv_I, 3l1p_A, 2hos_A, 1fjl_B, 5zjt_E, 7psx_B, 5hod_A, 1ig7_A, 6a8r_A, 3a01_E, 1b72_A, 7xrc_C, 1e3o_C, 1au7_A, 2xsd_C, 1le8_A, 1le8_B, 1du0_A, 1mnm_C, 1puf_B, 1k61_B, 8g87_X, 4qtr_D, 1o4x_A, 4xrm_B
Binding Motifs: MA0924.1 GYAATwAA
Publications: Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed]
Related annotations: PaperBLAST

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