Transcription Factor

Accessions: CAG47050 (JASPAR 2024)
Names: Q6FG54_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 441
Pfam Domains: 54-135 Sterile alpha motif (SAM)/Pointed domain
335-416 Ets-domain
Sequence:
(in bold interface residues)
1 MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFTKEQ 60
61 QRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDF 120
121 VGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSF 180
181 ITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGR 240
241 TSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKP 300
301 KGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLRQFLLELLTDKSCQSFISWTGDG 360
361 WEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQS 420
421 LLGYTPEELHAMLDVKPDADE
Interface Residues: 332, 387, 388, 390, 391, 392, 394, 395, 409
3D-footprint Homologues: 3zp5_A, 1dux_F, 7jsa_J, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C
Binding Motifs: MA0098.1 ywTCCk
Binding Sites: MA0098.1.1
MA0098.1.10
MA0098.1.11
MA0098.1.12
MA0098.1.13
MA0098.1.14
MA0098.1.15
MA0098.1.16
MA0098.1.17
MA0098.1.18
MA0098.1.19
MA0098.1.2
MA0098.1.20
MA0098.1.3
MA0098.1.4
MA0098.1.5
MA0098.1.6
MA0098.1.7
MA0098.1.8
MA0098.1.9
Publications: Woods D. B., Ghysdael J., Owen M. J. Identification of nucleotide preferences in DNA sequences recognised specifially by c-Ets-1 protein. Nucleic Acids Res. 20:699-704 (1992). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.