Transcription Factor
| Accessions: | DBP_HUMAN (HOCOMOCO 10), Q10586 (JASPAR 2024) |
| Names: | Albumin D box-binding protein, Albumin D-element-binding protein, D site-binding protein, DBP_HUMAN, Tax-responsive enhancer element-binding protein 302, TaxREB302 |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 325 |
| Pfam Domains: | 254-307 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 MARPVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPA 60 61 ATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLD 120 121 AFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASG 180 181 HRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPI 240 241 MKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQE 300 301 VVAVRQELSHYRAVLSRYQAQHGAL |
| Interface Residues: | 262, 265, 266, 268, 269, 272, 273 |
| 3D-footprint Homologues: | 6mg1_B, 1nwq_C, 1dh3_C, 2dgc_A |
| Binding Motifs: | MA0639.1 krTTAYRTAAya DBP_HUMAN.H10MO.B|M01074 rTTaTGyAAya MA0639.2 rTTAYRTAAy |
| Publications: | Xu Z, Kaga S, Tsubomizu J, Fujisaki J, Mochiduki A, Sakai T, Tsukamura H, Maeda K, Inoue K, Adachi AA. Circadian transcriptional factor DBP regulates expression of Kiss1 in the anteroventral periventricular nucleus. Mol Cell Endocrinol : (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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