Transcription Factor
| Accessions: | UP00329A (UniPROBE 20160601) |
| Names: | Aro80, D9461.10, Transcriptional activator ARO80, YDR421W |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q04052 |
| Description: | Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids |
| Length: | 116 |
| Pfam Domains: | 22-63 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 SAKKRPSGNAAFELPKRRRTYQACISCRSRKVKCDLGPVDNPHDPPCARCKRELKKCIFS 60 61 SNKGTSNDLPPNSINAISLPSLGKSKQEIQNDSTSPILSDVPLSRKGISSEKSFKS |
| Interface Residues: | 17, 18, 28, 30, 31, 32, 33, 52, 53 |
| 3D-footprint Homologues: | 1f5e_P, 1pyi_A, 6gys_C, 7uik_T, 1zme_D, 1d66_B, 3coq_A |
| Binding Motifs: | UP00329A_1 grkmawkCTCGGbwAkwawkh |
| Binding Sites: | ATGCCGAA ATTACCGA ATTCCCGA ATTGCCGA CCTCGGCA CTCGGCAA CTCGGGAA CTCGGTAA GCTCGGCA GCTCGGTA GTTGCCGA TCTCGGCA TTACCGAA TTCCCGAA TTCGGCAA ATGCCGAG ATTCGGCA CTTACCGA GTTCGGCA GTTCGGTA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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