Transcription Factor
| Accessions: | O77215 (JASPAR 2024) |
| Names: | DPHD-1, Homeobox protein unc-4, Paired-like homeodomain protein unc-4, UNC4_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O77215 |
| Length: | 588 |
| Pfam Domains: | 244-300 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MVLETSEGDTKKFLTNNNNSSASRNNNSHNNNNNNHSPKEIPEETGRSSSTSSNSIPNAH 60 61 RTNAGQHLLGGSPSSACSTSVSGCGMPSEGLHPTAALQLYAAAAQLAPNGVRVPPWGPFL 120 121 QFGVPGVFGPNGPFLGRPRFDAASAGGHPNSAAAAAAATQMAAVNASNAFANLTGLSAAA 180 181 LRNVSAAQTTAVAAVASTVATIQHRLMIGNRQSLPPAGPPSEGSNEDGGFPGDGDDDSSA 240 241 AKRRRSRTNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRK 300 301 REHTKKGPGRPAHNAQPQTCSGEPIPPNELKAKERARRRKKLAKAIDRQARKLQAKGITV 360 361 DLEALKAEYISQHKANGTFSDSDLEDDGIQIDVVGGTDSDDEGDSDAVSPVRLGGGGGGG 420 421 GGTGGGGGGGASSSLHCGLDGDGDSSRAGSFIGGGGSLGSPSSVAPPSMLSNGAVQFGKL 480 481 EPMDGNESEERDRERDSPKPLLFPAKAFHQLNLQSSQQHHGLVVGQGQGSGSGHGHGHQH 540 541 NHHQHHLHHGSASASAAAAVANLVHQTSPISMRRSNPFSIESLLFNNT |
| Interface Residues: | 243, 244, 245, 246, 247, 285, 286, 288, 289, 292, 293, 296, 297, 300 |
| 3D-footprint Homologues: | 4j19_B, 3a01_E, 1fjl_B, 2h1k_B, 1ig7_A, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 5zfz_A, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 2ld5_A, 7q3o_C, 6es3_K, 4cyc_A, 5flv_I, 3l1p_A, 1b72_A, 5zjt_E, 7psx_B, 5hod_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 1au7_A, 2xsd_C, 1e3o_C, 7xrc_C, 1o4x_A, 8g87_X, 1du0_A, 4qtr_D |
| Binding Motifs: | MA0250.1 tTAATTr |
| Binding Sites: | MA0250.1.11 MA0250.1.20 MA0250.1.5 MA0250.1.1 MA0250.1.12 / MA0250.1.9 MA0250.1.19 MA0250.1.6 MA0250.1.10 MA0250.1.13 MA0250.1.14 MA0250.1.15 MA0250.1.16 MA0250.1.17 MA0250.1.18 MA0250.1.2 MA0250.1.3 MA0250.1.4 MA0250.1.7 MA0250.1.8 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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