Transcription Factor

Accessions: T085229_1.02 (CISBP 1.02), Q02710 (JASPAR 2024)
Names: ECM23, T085229_1.02;, ECM23_YEAST, Extracellular mutant protein 23, Protein ECM23, SRD1 homolog 2
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:GATA
Length: 187
Pfam Domains: 132-166 GATA zinc finger
Sequence:
(in bold interface residues)
1 MLYNKEQGTSGASSSGRRTKFHFDRFVQMVLFIAANPNYCCSVASIPKSGVTPDLKRADI 60
61 LEQKIKSLNSALSPKLKEESRLGGPLHNPSILPAPSFSSLPISSNGKKSLAGYRPKSRKK 120
121 QTILPNGQPKECATCGDTWTSQWRSGPNGNVELCSRCGIAYRKKMEKKIRSQQSSDDGTK 180
181 NFIFKNK
Interface Residues: 141, 142, 144, 155, 159
3D-footprint Homologues: 1gat_A, 3dfx_B, 3vd6_C, 4gat_A
Binding Motifs: M0806_1.02 aAGATCyr
MA0293.1 mmAGATCtwam
MA0293.2 AGATC
Publications: Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.