Transcription Factor

						

			
Accessions: CREB3_full (HumanTF 1.0)

			
Names: CREB3, CREB3 regulatory factor, CRERF_HUMAN, LRF, Luman recruitment factor
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q8IUR6
Notes: Ensembl ID: ENSG00000107175; Full protein sequence; TF family: bZIP; Clone source: hORFeome
Length: 372
Pfam Domains:   150-209 bZIP transcription factor
  152-201 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 MELELDAGDQDLLAFLLEESGDLGTAPDEAVRAPLDWALPLSEVPSDWEVDDLLCSLLSP   60
  61 PASLNILSSSNPCLVHHDHTYSLPRETVSMDLESESCRKEGTQMTPQHMEELAEQEIARL  120
 121 VLTDEEKSLLEKEGLILPETLPLTKTEEQILKRVRRKIRNKRSAQESRRKKKVYVGGLES  180
 181 RVLKYTAQNMELQNKVQLLEEQNLSLLDQLRKLQAMVIEISNKTSSSSTCILVLLVSFCL  240
 241 LLVPAMYSSDTRGSLPAEHGVLSRQLRALPSEDPYQLELPALQSEVPKDSTHQWLDGSDC  300
 301 VLQAPGNTSCLLHYMPQAPSAEPPLEWPFPDLFSEPLCRGPILPLQANLTRKGGWLPTGS  360
 361 PSVILQDRYSG*
Interface Residues: 157, 160, 161, 163, 164, 167, 168
3D-footprint Homologues: 6mg1_B, 1dh3_C, 5t01_B, 5vpe_D
Binding Motifs: CREB3_full_1 ygrTGACGTCAyCm
CREB3_full_2 rtGmCACGTCAycr
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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