Transcription Factor

Accessions: ATF6B (HT-SELEX2 May2017)
Names: ATF6B, ENSG00000213676
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3
Length: 95
Pfam Domains: 17-78 bZIP transcription factor
20-69 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 VPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAVLADNQQL 60
61 RRENAALRRRLEALLAENSELKLGSGNRKVVCIMV
Interface Residues: 24, 28, 31, 32, 35, 36
3D-footprint Homologues: 7x5e_E, 5t01_B, 1dh3_C
Binding Motifs: ATF6B_3 tGCCACGTCAyc
ATF6B_4 grTGACGTCAyc
ATF6B_5 yGCCACGTGGCA
ATF6B_methyl_1 yGCCACGTCAyc
ATF6B_methyl_2 grTGACGTCAyc
Related annotations: PaperBLAST

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