Transcription Factor

Accessions: ATHB1 (Athamap 20091028), Q02283 (JASPAR 2024), T14465 (AthalianaCistrome v4_May2016)
Names: ATHB1, HAT5_ARATH, HD-ZIP protein 5, HD-ZIP protein ATHB-1, Homeobox-leucine zipper protein HAT5, Homeodomain transcription factor ATHB-1, Homeodomain-leucine zipper protein HAT5, AT3G01470, HAT5, T14465;
Organisms: Arabidopsis thaliana
Libraries: Athamap 20091028 1, JASPAR 2024 2, AthalianaCistrome v4_May2016 3
1 Bulow L, Engelmann S, Schindler M, Hehl R. AthaMap, integrating transcriptional and post-transcriptional data. Nucleic acids research 37:D983-6 (2009). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
3 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:Homeobox
Length: 272
Pfam Domains: 68-121 Homeobox domain
123-167 Homeobox associated leucine zipper
Sequence:
(in bold interface residues)
1 MESNSFFFDPSASHGNSMFFLGNLNPVVQGGGARSMMNMEETSKRRPFFSSPEDLYDDDF 60
61 YDDQLPEKKRRLTTEQVHLLEKSFETENKLEPERKTQLAKKLGLQPRQVAVWFQNRRARW 120
121 KTKQLERDYDLLKSTYDQLLSNYDSIVMDNDKLRSEVTSLTEKLQGKQETANEPPGQVPE 180
181 PNQLDPVYINAAAIKTEDRLSSGSVGSAVLDDDAPQLLDSCDSYFPSIVPIQDNSNASDH 240
241 DNDRSCFADVFVPTTSPSHDHHGESLAFWGWP
Interface Residues: 64, 68, 69, 70, 71, 107, 108, 110, 111, 114, 115, 118, 119, 122, 262, 264
3D-footprint Homologues: 3a01_E, 1zq3_P, 5jlw_D, 4cyc_A, 2r5y_A, 1puf_B, 6es3_K, 1b72_A, 5zfz_A, 7q3o_C, 1puf_A, 6a8r_A, 2ld5_A, 3d1n_M, 1au7_A, 1nk2_P, 1le8_A, 1ig7_A, 6ryd_F, 7xrc_C, 1e3o_C, 6wig_A, 8g87_X, 1fjl_B, 5flv_I, 3l1p_A, 7psx_B, 4qtr_D, 5hod_A, 3lnq_A, 1o4x_A, 1du0_A, 5zjt_E, 4xrm_B, 3cmy_A, 2h1k_B, 1jgg_B, 3rkq_B, 2lkx_A, 4xrs_G, 2hdd_A, 2hos_A, 6m3d_C, 5itu_A
Binding Motifs: ATHB1 cAATTATTG
MA0008.1 cAATTATT
MA0008.2 ytcAATTATTGs
M0441 wwcAATAATTgaww
M0442 wyAATAATTrw
MA0008.3 wwwCAATWATTGaww
MA0008.4 CAATWATTG
Binding Sites: MA0008.4.19
MA0008.1.1
MA0008.1.10
MA0008.1.11
MA0008.1.12
MA0008.1.13
MA0008.1.14
MA0008.1.15
MA0008.1.16
MA0008.1.17
MA0008.1.18
MA0008.1.19
MA0008.1.2
MA0008.1.20
MA0008.1.3
MA0008.1.4
MA0008.1.5
MA0008.1.6
MA0008.1.7
MA0008.1.8
MA0008.1.9
MA0008.3.1
MA0008.3.10
MA0008.3.11
MA0008.3.12
MA0008.3.13
MA0008.3.14
MA0008.3.15
MA0008.3.16
MA0008.3.17
MA0008.3.18
MA0008.3.19
MA0008.3.2
MA0008.3.20
MA0008.3.3
MA0008.3.4
MA0008.3.5
MA0008.3.6
MA0008.3.7
MA0008.3.8
MA0008.3.9
MA0008.4.1 / MA0008.4.14
MA0008.4.10 / MA0008.4.13 / MA0008.4.16 / MA0008.4.18 / MA0008.4.5 / MA0008.4.7 / MA0008.4.8
MA0008.4.11 / MA0008.4.12 / MA0008.4.15 / MA0008.4.17 / MA0008.4.4 / MA0008.4.6 / MA0008.4.9
MA0008.4.2
MA0008.4.20 / MA0008.4.3
Publications: Sessa G., Morelli G., Ruberti I. The Athb-1 and -2 HD-Zip domains homodimerize forming complexes of different DNA binding specificities. EMBO J. 12:3507-3517 (1993). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.