Transcription Factor
| Accessions: | O43248 (JASPAR 2024) |
| Names: | Homeobox protein Hox-3H, Homeobox protein Hox-C11, HXC11_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 304 |
| Pfam Domains: | 42-178 Protein of unknown function (DUF3528) 233-289 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYMPEFSTVSSFLPQAPSRQIS 60 61 YPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGS 120 121 YGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGE 180 181 PEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYS 240 241 KFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSG 300 301 NPLL |
| Interface Residues: | 233, 234, 235, 236, 274, 275, 277, 278, 281, 282, 285, 286, 289 |
| 3D-footprint Homologues: | 6a8r_A, 1fjl_B, 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 3cmy_A, 3lnq_A, 1nk2_P, 1zq3_P, 2lkx_A, 2ld5_A, 2r5y_A, 1puf_B, 7psx_B, 5jlw_D, 2hos_A, 6es3_K, 4xrs_G, 7q3o_C, 1b72_A, 3rkq_B, 5flv_I, 3a01_E, 5zjt_E, 4cyc_A, 1jgg_B, 6m3d_C, 2hdd_A, 1e3o_C, 1au7_A, 2xsd_C, 1le8_A, 7xrc_C, 4qtr_D, 1k61_B, 1o4x_A, 6fqq_E, 1le8_B, 1du0_A, 5hod_A, 1mnm_C |
| Binding Motifs: | MA0651.1 rrTCGTWAAah MA0651.2 arGTCGTAAAAh MA0651.3 arGTCGTAAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.