Transcription Factor

Accessions: T012439_1.02 (CISBP 1.02), Q8GZ38 (JASPAR 2024)
Names: T012439_1.02;, UNE10, AtbHLH16, Basic helix-loop-helix protein 16, bHLH 16, bHLH transcription factor bHLH016, Protein UNFERTILIZED EMBRYO SAC 10, Transcription factor EN 108, Transcription factor UNE10, UNE10_ARATH
Organisms: Arabidopsis thaliana
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 399
Pfam Domains: 218-263 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MSQCVPNCHIDDTPAAATTTVRSTTAADIPILDYEVAELTWENGQLGLHGLGPPRVTASS 60
61 TKYSTGAGGTLESIVDQATRLPNPKPTDELVPWFHHRSSRAAMAMDALVPCSNLVHEQQS 120
121 KPGGVGSTRVGSCSDGRTMGGGKRARVAPEWSGGGSQRLTMDTYDVGFTSTSMGSHDNTI 180
181 DDHDSVCHSRPQMEDEEEKKAGGKSSVSTKRSRAAAIHNQSERKRRDKINQRMKTLQKLV 240
241 PNSSKTDKASMLDEVIEYLKQLQAQVSMMSRMNMPSMMLPMAMQQQQQLQMSLMSNPMGL 300
301 GMGMGMPGLGLLDLNSMNRAAASAPNIHANMMPNPFLPMNCPSWDASSNDSRFQSPLIPD 360
361 PMSAFLACSTQPTTMEAYSRMATLYQQMQQQLPPPSNPK
Interface Residues: 212, 216, 217, 218, 219, 221, 222, 225, 226, 248
3D-footprint Homologues: 5sy7_B, 7z5k_B, 1an4_A, 7d8t_A, 5eyo_A, 7xi3_A, 4h10_A, 7f2f_B, 5gnj_I, 1a0a_B, 5v0l_A, 7rcu_E, 5i50_B, 6g1l_A, 4zpk_A, 7ssa_L, 5nj8_D, 4h10_B, 2ql2_D, 8osl_P, 8osl_O
Binding Motifs: M0158_1.02 cCACGTGm
MA1074.1 cCACGTGm
MA1074.2 CACGTGm
Publications: Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico J.M, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla J.M, Pauwels L, Witters E, Puga M.I, Paz-Ares J, Goossens A, Reymond P, De Jaeger G, Solano R. The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses. The Plant cell 23:701-15 (2011). [Pubmed]
Related annotations: PaperBLAST

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