Transcription Factor

Accessions: Q3UHV1 (JASPAR 2024)
Names: Q3UHV1_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q3UHV1
Length: 524
Pfam Domains: 211-229 Zinc-finger double domain
218-239 C2H2-type zinc finger
219-241 Zinc finger, C2H2 type
219-241 C2H2-type zinc finger
233-256 Zinc-finger double domain
247-265 C2H2-type zinc finger
247-269 Zinc finger, C2H2 type
261-286 Zinc-finger double domain
275-297 C2H2-type zinc finger
275-295 C2H2-type zinc finger
275-297 Zinc finger, C2H2 type
289-314 Zinc-finger double domain
302-325 C2H2-type zinc finger
303-325 C2H2-type zinc finger
303-325 Zinc finger, C2H2 type
318-342 Zinc-finger double domain
331-353 C2H2-type zinc finger
331-351 C2H2-type zinc finger
331-353 Zinc finger, C2H2 type
345-370 Zinc-finger double domain
359-381 C2H2-type zinc finger
359-381 C2H2-type zinc finger
359-381 Zinc finger, C2H2 type
373-398 Zinc-finger double domain
386-407 C2H2-type zinc finger
387-409 C2H2-type zinc finger
387-409 Zinc finger, C2H2 type
402-425 Zinc-finger double domain
415-435 C2H2-type zinc finger
415-437 Zinc finger, C2H2 type
415-437 C2H2-type zinc finger
432-454 Zinc-finger double domain
443-457 C2H2-type zinc finger
443-465 Zinc finger, C2H2 type
443-465 C2H2-type zinc finger
458-481 Zinc-finger double domain
471-493 C2H2-type zinc finger
471-493 Zinc finger, C2H2 type
471-493 C2H2-type zinc finger
485-508 Zinc-finger double domain
498-510 C2H2-type zinc finger
499-521 C2H2-type zinc finger
499-521 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MTTELKETMGRASWDPEKVKMEEDDESVISQASSQQVYYENDKDCAPGEGPYGSISVSED 60
61 EEKGQEMFREMAVVLKATQEAAAASPFGSYSLAGTLAESQILELHGKPTPTGAKSKNLEL 120
121 LIPKKEISDDSEKPPMILGRIQKGDLQGPELGESCEKGNVLKGLRIKEEKGDLGEATVKD 180
181 CPLSESFRDEEESKKSRGKYSLRSTPGKNQKIQPGQKPFTCSECGKGFSQSANLVVHQRI 240
241 HTGEKPFECHECGKAFIQSANLVVHQRIHTGQKPYVCGKCGKAFTQSSNLTVHQKIHSLE 300
301 KTFKCSECEKAFSYSSQLARHQKVHITEKCYECNECGKTFTRSSNLIVHQRIHTGEKPFA 360
361 CSDCGKAFTQSANLIVHQRSHTGEKPYKCKDCEKAFSCFSHLIVHQRIHTAEKPYDCSEC 420
421 GKAFSQLSCLIVHQRIHSGDLPYVCNECGKAFTCSSYLLIHQRIHNGEKPYSCNECGKAF 480
481 RQRSSLTVHQRTHTGEKPYECAKCGAAFISNSHLMRHHRTHLVE
Interface Residues: 230, 232, 233, 236, 240, 257, 258, 259, 260, 261, 263, 264, 285, 286, 287, 288, 289, 292, 296, 303, 313, 314, 315, 316, 317, 319, 320, 341, 342, 343, 344, 345, 347, 348, 350, 351, 354, 369, 370, 371, 372, 373, 376, 380, 397, 398, 399, 400, 401, 402, 404, 407, 425, 426, 427, 428, 429, 431, 432, 435, 438, 452, 453, 454, 455, 456, 457, 459, 460, 464, 481, 482, 483, 484, 485, 488, 489, 510, 511, 512, 513, 514, 515, 516, 517
3D-footprint Homologues: 1mey_C, 1f2i_J, 5k5i_A, 8ssq_A, 7w1m_H, 5und_A, 1g2f_F, 8ssu_A, 4x9j_A, 1llm_D, 5kkq_D, 1ubd_C, 6e94_A, 6ml4_A, 6u9q_A, 5yel_A, 2kmk_A, 7n5w_A, 2drp_D, 5v3j_F, 8gn3_A, 8h9h_G, 7eyi_G, 7ysf_A, 8cuc_F, 7y3l_A, 7txc_E, 5kl3_A, 2gli_A, 5k5l_F, 2i13_A, 6blw_A, 7y3m_I, 2jpa_A, 1tf3_A, 1tf6_A, 2wbs_A, 6wmi_A, 5ei9_F, 6jnm_A, 2lt7_A, 6a57_A, 3uk3_C, 4m9v_C, 5yj3_D
Binding Motifs: PB0093.1 wayAAwhAAmAAkar
PB0197.1 dyggkTCAATAAytykr
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.