Transcription Factor

Accessions: P10181 (JASPAR 2024)
Names: ROUGH_DROME
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P10181
Length: 350
Pfam Domains: 192-248 Homeobox domain
Sequence:
(in bold interface residues)
1 MQRHKVEIGSPDGSPGIKRSDSLDPIANTTILSVPQRPSSPRQFFERLYGHLETRSSENG 60
61 EIDVGTHAHKPPPCDTPYHSDGGSVSSPDISISDERTSLAAYPAYDFYGHAKDYPQHPSQ 120
121 QHQQHHHHHHHPPQLVHQKLSYVSPPPAIAAGGAANPVLPHAFPAGFPSDPHFSAGFSAF 180
181 LARRRRKEGRQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQ 240
241 NRRAKDKRIEKAQIDQHYRNFVVANGFMSSIMGQAATTMPPGGVTGGVAVGVGLNYYAAA 300
301 ATPAALPKDNTQDANFIDIDDQFQRQQQQKQQQQQQQQRRRETTTPINIC
Interface Residues: 158, 160, 162, 169, 170, 175, 177, 190, 191, 192, 193, 194, 195, 205, 207, 233, 234, 236, 237, 240, 241, 244, 245, 248, 249
3D-footprint Homologues: 5tkz_B, 1au7_A, 6fqp_B, 4j19_B, 1ig7_A, 5zfz_A, 2h1k_B, 1puf_A, 3cmy_A, 6a8r_A, 3d1n_M, 1fjl_B, 3lnq_A, 2lkx_A, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 2ld5_A, 7q3o_C, 6es3_K, 3a01_E, 5hod_A, 5zjt_E, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 7psx_B, 4cyc_A, 1b72_A, 5flv_I, 3l1p_A, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1o4x_A, 1le8_B, 1du0_A, 4qtr_D, 1mnm_C, 8g87_X, 1k61_B
Binding Motifs: MA0241.1 yTAATTA
Binding Sites: MA0241.1.12
MA0241.1.11
MA0241.1.9
MA0241.1.4
MA0241.1.1
MA0241.1.15
MA0241.1.16
MA0241.1.6
MA0241.1.13
MA0241.1.17 / MA0241.1.18 / MA0241.1.19
MA0241.1.10
MA0241.1.3 / MA0241.1.8
MA0241.1.14
MA0241.1.2
MA0241.1.20
MA0241.1.5
MA0241.1.7
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.