Transcription Factor
| Accessions: | ZNF41 (humanC2H2ZF-ChIP Feb2015) |
| Names: | ENSG00000147124, P51814, ZNF41 |
| Organisms: | Homo sapiens |
| Libraries: | humanC2H2ZF-ChIP Feb2015 1 1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] |
| Notes: | TF family: C2H2;KRAB experiment: ChIP-seq/MEME/B1H-RC |
| Length: | 821 |
| Pfam Domains: | 69-109 KRAB box 313-335 Zinc finger, C2H2 type 313-335 C2H2-type zinc finger 363-379 Zinc-finger double domain 369-391 C2H2-type zinc finger 369-391 Zinc finger, C2H2 type 369-389 C2H2-type zinc finger 383-406 Zinc-finger double domain 396-406 C2H2-type zinc finger 397-419 C2H2-type zinc finger 397-419 Zinc finger, C2H2 type 412-435 Zinc-finger double domain 424-435 C2H2-type zinc finger 425-447 Zinc finger, C2H2 type 425-447 C2H2-type zinc finger 439-464 Zinc-finger double domain 453-473 C2H2-type zinc finger 453-475 Zinc finger, C2H2 type 453-475 C2H2-type zinc finger 467-490 Zinc-finger double domain 481-503 Zinc finger, C2H2 type 481-503 C2H2-type zinc finger 495-519 Zinc-finger double domain 508-519 C2H2-type zinc finger 509-531 Zinc finger, C2H2 type 509-531 C2H2-type zinc finger 527-548 Zinc-finger double domain 537-559 C2H2-type zinc finger 537-559 Zinc finger, C2H2 type 537-559 C2H2-type zinc finger 551-575 Zinc-finger double domain 565-587 Zinc finger, C2H2 type 567-587 C2H2-type zinc finger 567-587 C2H2-type zinc finger 579-602 Zinc-finger double domain 593-615 C2H2-type zinc finger 593-615 Zinc finger, C2H2 type 608-630 Zinc-finger double domain 621-630 C2H2-type zinc finger 621-643 Zinc finger, C2H2 type 636-658 Zinc-finger double domain 649-671 Zinc finger, C2H2 type 666-687 Zinc-finger double domain 676-697 C2H2-type zinc finger 677-699 Zinc finger, C2H2 type 677-699 C2H2-type zinc finger 692-715 Zinc-finger double domain 707-727 Zinc finger, C2H2 type 707-727 C2H2-type zinc finger 707-725 C2H2-type zinc finger 719-743 Zinc-finger double domain 732-742 C2H2-type zinc finger 733-755 Zinc finger, C2H2 type 733-755 C2H2-type zinc finger 748-770 Zinc-finger double domain 761-770 C2H2-type zinc finger 761-783 Zinc finger, C2H2 type 761-783 C2H2-type zinc finger 776-799 Zinc-finger double domain 789-812 C2H2-type zinc finger 789-811 Zinc finger, C2H2 type 789-811 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MAANGDSPPWSPALAAEGRGSSCEVRRERTPEARIHSVKRYPDLSPGPKGRSSADHAALN 60 61 SIVSLQASVSFEDVTVDFSKEEWQHLDPAQRRLYWDVTLENYSHLLSVGYQIPKSEAAFK 120 121 LEQGEGPWMLEGEAPHQSCSGEAIGKMQQQGIPGGIFFHCERFDQPIGEDSLCSILEELW 180 181 QDNDQLEQRQENQNNLLSHVKVLIKERGYEHKNIEKIIHVTTKLVPSIKRLHNCDTILKH 240 241 TLNSHNHNRNSATKNLGKIFGNGNNFPHSPSSTKNENAKTGANSCEHDHYEKHLSHKQAP 300 301 THHQKIHPEEKLYVCTECVMGFTQKSHLFEHQRIHAGEKSRECDKSNKVFPQKPQVDVHP 360 361 SVYTGEKPYLCTQCGKVFTLKSNLITHQKIHTGQKPYKCSECGKAFFQRSDLFRHLRIHT 420 421 GEKPYECSECGKGFSQNSDLSIHQKTHTGEKHYECNECGKAFTRKSALRMHQRIHTGEKP 480 481 YVCADCGKAFIQKSHFNTHQRIHTGEKPYECSDCGKSFTKKSQLHVHQRIHTGEKPYICT 540 541 ECGKVFTHRTNLTTHQKTHTGEKPYMCAECGKAFTDQSNLIKHQKTHTGEKPYKCNGCGK 600 601 AFIWKSRLKIHQKSHIGERHYECKDCGKAFIQKSTLSVHQRIHTGEKPYVCPECGKAFIQ 660 661 KSHFIAHHRIHTGEKPYECSDCGKCFTKKSQLRVHQKIHTGEKPNICAECGKAFTDRSNL 720 721 ITHQKIHTREKPYECGDCGKTFTWKSRLNIHQKSHTGERHYECSKCGKAFIQKATLSMHQ 780 781 IIHTGKKPYACTECQKAFTDRSNLIKHQKMHSGEKRYKASD |
| Interface Residues: | 369, 379, 380, 381, 382, 383, 386, 390, 407, 408, 409, 410, 411, 414, 418, 435, 436, 437, 438, 439, 441, 442, 464, 465, 466, 467, 469, 470, 473, 491, 492, 493, 494, 495, 497, 498, 500, 501, 504, 519, 520, 521, 522, 523, 524, 525, 526, 547, 548, 549, 550, 551, 553, 554, 555, 558, 575, 576, 577, 578, 579, 580, 582, 583, 604, 605, 606, 607, 609, 610, 611, 613, 631, 632, 634, 635, 638, 659, 660, 662, 663, 666, 688, 689, 690, 691, 694, 696, 728, 742, 744, 746, 747, 750, 754, 771, 772, 773, 775, 800 |
| 3D-footprint Homologues: | 2kmk_A, 6jnm_A, 5kkq_D, 8ssu_A, 1tf6_A, 4x9j_A, 8gn3_A, 2wbs_A, 1mey_C, 1f2i_J, 5k5i_A, 8ssq_A, 5und_A, 2i13_A, 5yel_A, 3uk3_C, 1llm_D, 7eyi_G, 6ml4_A, 5v3j_F, 5yj3_D, 1ubd_C, 7n5w_A, 2lt7_A, 6blw_A, 5ei9_F, 6wmi_A, 1g2f_F, 8h9h_G, 6a57_A, 2jpa_A, 7y3l_A, 1tf3_A, 8cuc_F, 5k5l_F, 5kl3_A, 7w1m_H, 2gli_A, 7y3m_I, 6e94_A, 6u9q_A, 7txc_E, 2drp_D, 4m9v_C, 7ysf_A |
| Binding Motifs: | ZNF41_ChIP GGrArtaarsCACCA |
| Related annotations: | PaperBLAST |
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