Transcription Factor

Accessions: Q63245 (JASPAR 2024)
Names: Forkhead box protein D3, FOXD3_RAT, Fragment, Hepatocyte nuclear factor 3 forkhead homolog 2, HFH-2, HNF3/FH transcription factor genesis
Organisms: Rattus norvegicus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 101
Pfam Domains: 3-98 Fork head domain
Sequence:
(in bold interface residues)
1 LVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDC 60
61 FVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKR
Interface Residues: 46, 48, 49, 50, 52, 53, 54, 56, 57, 66, 73, 95, 98
3D-footprint Homologues: 7vox_H, 2hdc_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 3qrf_G
Binding Motifs: MA0041.1 gwwTRTTTdTTY
Binding Sites: MA0041.1.10
MA0041.1.18
MA0041.1.1 / MA0041.1.2
MA0041.1.13
MA0041.1.12
MA0041.1.17
MA0041.1.15
MA0041.1.14
MA0041.1.9
MA0041.1.3 / MA0041.1.4 / MA0041.1.5 / MA0041.1.6 / MA0041.1.7 / MA0041.1.8
MA0041.1.19 / MA0041.1.20
MA0041.1.11
MA0041.1.16
Publications: Overdier D. G., Porcella A., Costa R. H. The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino acid residues adjacent to the recognition helix. Mol. Cell. Biol. 14:2755-2766 (1994). [Pubmed]
Related annotations: PaperBLAST

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