Transcription Factor

						

			
Accessions: JUNB (SMILE-seq 1.0)

			
Names: JUNB, JUNB_HUMAN
Organisms: Homo sapiens
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: P17275
Notes: TF family: bZIP
Length: 346
Pfam Domains:     5-257 Jun-like transcription factor
  266-329 bZIP transcription factor
  273-326 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKPSLAVNLADPYRSLKAPGARGPGP   60
  61 EGGGGGSYFSGQGSDTGASLKLASSELERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGG  120
 121 AGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGATGGPPAGPGGVYAGPEPPP  180
 181 VYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFK  240
 241 EEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKV  300
 301 KTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHA
Interface Residues: 263, 264, 267, 268, 274, 275, 277, 278, 279, 281, 282, 285, 286, 289
3D-footprint Homologues: 5i50_B, 1gd2_G, 7x5e_E, 2wt7_B, 1skn_P, 7x5e_F, 4eot_A, 2wt7_A, 6mg1_B, 5t01_B, 5vpe_C, 5vpe_D, 2dgc_A
Binding Motifs: JUNB_1 aTGACTCA
JUNB_2 rTkACGTmAy
JUNB_FOSB_1 krTGAsTCAy
JUNB_FOSB_2 rTGACGTCAy
JUNB_FOSL1_1 ykrTGAcTMAtmc
JUNB_FOSL2_1 krTGAsTCAy
JUNB_FOSL2_2 krTGACGTCAym
JUNB_FOS_1 krTGAsTCAymv
JUN_JUNB_1 kaTGACkCAt
JUN_JUNB_2 krTGACGTCATb
			
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.