Transcription Factor

Accessions: UP00138A (UniPROBE 20160601)
Names: brain specific homeobox, Brain-specific homeobox protein homolog, Bsx, MGC129478, MGC129479
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q810B3
Description: brain specific homeobox
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 FPHPQHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQV 60
61 KTWFQNRRMKHKKQLRKSQDEPKAADGPESPEG
Interface Residues: 16, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 4j19_B, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1fjl_B, 5zfz_A, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 1zq3_P, 2ld5_A, 7q3o_C, 6es3_K, 1b72_A, 5flv_I, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1au7_A, 4xrs_G, 2hos_A, 4cyc_A, 6m3d_C, 1e3o_C, 7xrc_C, 2xsd_C, 1le8_A, 3l1p_A, 1o4x_A, 8g87_X, 1le8_B, 1du0_A, 4qtr_D, 1mnm_C, 1puf_B, 1k61_B
Binding Motifs: UP00138A_1 vmrgyAATTrsytsAd
Binding Sites: GGTAATTA
AATAATTA
ACCAATTA
ACCCATTA
ACCGATTA
ACTAATTA
AGTAATTA
ATAATTAC
ATCAATTA
ATCGATTA
ATTAATTA
ATTAATTG
CTAATTAA
CTAATTAG
GATAATTA
GCAATTAA
GCTAATTA
GTAATTAA
GTAATTAC
GTTAATTA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.