Transcription Factor

Accessions: T146242_1.02 (CISBP 1.02), Q02486 (JASPAR 2018)
Names: ABF2, T146242_1.02;, ABF2_YEAST
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, JASPAR 2018 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Cheneby , Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A (2017) JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic Acids Res. doi: 10.1093/nar/gkx1126 [Pubmed]
Notes: experiment type:PBM, family:Sox
Length: 183
Pfam Domains: 43-110 HMG (high mobility group) box
43-105 Domain of unknown function (DUF1898)
116-181 HMG (high mobility group) box
(in bold interface residues)
181 PLN
Interface Residues: 45, 48, 50, 51, 54, 58, 69, 70, 71, 73, 74, 105, 108, 118, 121, 123, 124, 127, 131, 142, 143, 144, 147
3D-footprint Homologues: 3f27_D, 4s2q_D, 1qrv_A, 1gt0_D, 4y60_C, 2gzk_A, 3u2b_C, 1j47_A, 1j5n_A, 4qr9_A, 2lef_A, 3tq6_B
Binding Motifs: M1614_1.02 asTCTAGAGcg
MA0266.1 sTCTAGA
Publications: Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed]
Related annotations: PaperBLAST


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