Transcription Factor
Accessions: | T012791_1.02 (CISBP 1.02), Q18053 (JASPAR 2024) |
Names: | hlh-26, T012791_1.02;, HLH26_CAEEL |
Organisms: | Caenorhabditis elegans |
Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | experiment type:PBM, family:bHLH |
Length: | 210 |
Pfam Domains: | 20-65 Helix-loop-helix DNA-binding domain |
Sequence: (in bold interface residues) | 1 MSSSPTSSSSGSPSSHGHRSETEKQRRDDTNDLLNEFKKIVQKSESEKLSKEEVLFRIVK 60 61 LLSGIQLHHESFSTSPGPIRSIKKIKSDREQVRRNKRVAAYRELRKFIALNNLSSSEEID 120 121 KMENLKVLEIIFEVIRGKSITCTVPCLPFPILPFLPVFPVYSPLVFNSYNQFSLYPPHMP 180 181 TVQIPIVPSSSFEIDALEIEENEKDIDIVG |
Interface Residues: | 20, 22, 23, 26, 27 |
3D-footprint Homologues: | 4h10_A, 8osl_P |
Binding Motifs: | PL0009.1 tawgrCACGTGTCywaw M0171_1.02 rACACGTGy UN0705.1 rACACGTGy |
Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] |
Related annotations: | PaperBLAST |
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