Transcription Factor
| Accessions: | Q8TAU0 (JASPAR 2024) |
| Names: | Homeobox protein NK-2 homolog C, Homeobox protein Nkx-2.3, NKX23_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8TAU0 |
| Length: | 364 |
| Pfam Domains: | 149-205 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MMLPSPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGE 60 61 EDEEDEGEKLSYLNSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQK 120 121 SCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREH 180 181 LASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKPCVT 240 241 PSAQAYGAPYSVGASAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSSSYGCAYPAGGG 300 301 GGGGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSGGSAQPLHQGTAAGAACAQGTLQG 360 361 IRAW |
| Interface Residues: | 120, 148, 149, 150, 151, 152, 190, 191, 193, 194, 197, 198, 201, 202, 205, 236 |
| 3D-footprint Homologues: | 1au7_A, 5zfz_A, 4j19_B, 1ig7_A, 2h1k_B, 1puf_A, 5zjt_E, 3cmy_A, 6a8r_A, 3d1n_M, 1fjl_B, 6m3d_C, 2lkx_A, 1nk2_P, 1zq3_P, 1puf_B, 7q3o_C, 6es3_K, 2ld5_A, 3a01_E, 5flv_I, 3lnq_A, 1jgg_B, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 2hos_A, 5jlw_D, 4cyc_A, 1b72_A, 4xrs_G, 1e3o_C, 2xsd_C, 1le8_A, 7xrc_C, 1le8_B, 1du0_A, 4qtr_D, 1mnm_C, 8g87_X, 1k61_B, 4xrm_B, 3l1p_A, 1o4x_A, 8f69_A |
| Binding Motifs: | MA0672.1 asCACTTrav MA0672.2 sCACTTra |
| Publications: | Kasahara H., Usheva A., Ueyama T., Aoki H., Horikoshi N., Izumo S. Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein. J. Biol. Chem. 276:4570-4580 (2001). [Pubmed] |
| Related annotations: | PaperBLAST |
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