Transcription Factor
| Accessions: | UP00325A (UniPROBE 20160601), P11633 (JASPAR 2024) |
| Names: | Nhp6b, NHPB, Nonhistone chromosomal protein 6B, YBR089C-A, YBR090BC, NHP6B_YEAST |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Description: | High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Ap; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to ce... |
| Length: | 99 |
| Pfam Domains: | 24-90 Domain of unknown function (DUF1898) 27-95 HMG (high mobility group) box |
| Sequence: (in bold interface residues) | 1 MAATKEAKQPKEPKKRTTRRKKDPNAPKRGLSAYMFFANENRDIVRSENPDVTFGQVGRI 60 61 LGERWKALTAEEKQPYESKAQADKKRYESEKELYNATRA |
| Interface Residues: | 14, 16, 17, 19, 29, 32, 34, 35, 38, 42, 53, 54, 55, 58 |
| 3D-footprint Homologues: | 2gzk_A, 1j5n_A, 4y60_C, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 3tq6_B, 1hry_A, 1ckt_A, 7zie_A |
| Binding Motifs: | MA0346.1 yttwyywwTATAwwwwrkdv UP00325A_1 yttwyywwTATAwwwwrkdv |
| Binding Sites: | AATATAAT AATATATA AATTAATA AATTATTA ATAATAAT ATAATTAA ATATAATA ATATATAA ATATATTA ATATTATA ATTAATTA TAATAATA TAATATAA TATATAAA TATATATA TATTAATA TTAATTAA TTATATAA ACATTATA ATAATGTA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] Newburger D.E, Bulyk M.L. UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic acids research 37:D77-82 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.