Transcription Factor

Accessions: GFI1B_MOUSE (HOCOMOCO 10), O70237 (JASPAR 2024)
Names: GFI1B_MOUSE, Growth factor independent protein 1B, Zinc finger protein Gfi-1b
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1, JASPAR 2024 2
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 330
Pfam Domains: 163-186 Zinc finger, C2H2 type
163-186 C2H2-type zinc finger
178-203 Zinc-finger double domain
192-210 Zinc-finger of C2H2 type
192-214 Zinc finger, C2H2 type
192-211 C2H2-type zinc finger
192-214 C2H2-type zinc finger
206-231 Zinc-finger double domain
220-242 C2H2-type zinc finger
220-242 Zinc finger, C2H2 type
220-238 C2H2-type zinc finger
235-258 Zinc-finger double domain
248-266 C2H2-type zinc finger
248-270 Zinc finger, C2H2 type
248-257 C2H2-type zinc finger
263-286 Zinc-finger double domain
275-298 C2H2-type zinc finger
276-298 C2H2-type zinc finger
276-298 Zinc finger, C2H2 type
290-313 Zinc-finger double domain
304-327 C2H2-type zinc finger
304-327 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MPRSFLVKSKKAHTYHQPRAQGDELVWPPAVIPVAKEHSQSASPLLSTPLPSQTLDWNTI 60
61 KQEREMLLNQSLPKMASAPEGPLVTPQPQDGESPLSESPPFYKPSFSWDTLASSYSHSYT 120
121 QTPSTMQSAFLERSVRLYGSPLVPSTESPLDFRLRYSPGMDTYHCVKCNKVFSTPHGLEV 180
181 HVRRSHSGTRPFACDVCGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLSTHLL 240
241 IHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTG 300
301 FKPFSCELCTKGFQRKVDLRRHRESQHNLK
Interface Residues: 147, 148, 174, 176, 177, 180, 200, 202, 203, 204, 205, 206, 208, 209, 210, 213, 220, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 243, 258, 259, 260, 261, 262, 264, 265, 268, 286, 287, 288, 289, 290, 292, 293, 314, 315, 316, 317, 318, 319, 320, 321, 325
3D-footprint Homologues: 5v3j_F, 8ssu_A, 6wmi_A, 5und_A, 5k5l_F, 8ssq_A, 1tf6_A, 7y3m_I, 8gh6_A, 5kkq_D, 6jnm_A, 5k5i_A, 7w1m_H, 4m9v_C, 7ysf_A, 2lt7_A, 2i13_A, 5yel_A, 6a57_A, 1ubd_C, 2kmk_A, 7n5w_A, 5ei9_F, 8gn3_A, 2drp_D, 6ml4_A, 8h9h_G, 7eyi_G, 6e94_A, 2jpa_A, 1tf3_A, 2wbs_A, 6u9q_A, 1mey_C, 7txc_E, 5kl3_A, 1f2i_J, 2gli_A, 1g2f_F, 4x9j_A, 6blw_A, 3uk3_C, 8cuc_F, 7y3l_A, 1llm_D, 5yj3_D
Binding Motifs: MA0483.1 aAATCwCwGCw
GFI1B_MOUSE.H10MO.C|M01126 GCwswGATTts
MA0483.2 aAATCwCwGC
Binding Sites: MA0483.1.1
MA0483.1.10
MA0483.1.11
MA0483.1.12
MA0483.1.13
MA0483.1.14
MA0483.1.15
MA0483.1.16
MA0483.1.17
MA0483.1.18
MA0483.1.19
MA0483.1.2
MA0483.1.20
MA0483.1.3
MA0483.1.4
MA0483.1.5
MA0483.1.6
MA0483.1.7
MA0483.1.8
MA0483.1.9
MA0483.2.1
MA0483.2.10
MA0483.2.11
MA0483.2.12
MA0483.2.13
MA0483.2.14
MA0483.2.15
MA0483.2.16
MA0483.2.17
MA0483.2.18
MA0483.2.19
MA0483.2.2
MA0483.2.20
MA0483.2.3
MA0483.2.4
MA0483.2.5
MA0483.2.6
MA0483.2.7
MA0483.2.8
MA0483.2.9
Publications: Anguita E, Villegas A, Iborra F, Hernández A. GFI1B controls its own expression binding to multiple sites. Haematologica 95:36-46 (2010). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.