Transcription Factor
| Accessions: | P09633 (JASPAR 2024) |
| Names: | Homeobox protein Hox-3.2, Homeobox protein Hox-C9, HXC9_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 260 |
| Pfam Domains: | 1-179 Hox9 activation region 193-249 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA 60 61 VFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKP 120 121 DAYPGRRADCGPGDGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPS 180 181 NPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWF 240 241 QNRRMKMKKMNKEKTDKEQS |
| Interface Residues: | 193, 194, 195, 196, 234, 235, 237, 238, 241, 242, 245, 246, 249 |
| 3D-footprint Homologues: | 6a8r_A, 2h1k_B, 5zfz_A, 1puf_A, 1fjl_B, 3cmy_A, 1ig7_A, 3d1n_M, 1nk2_P, 1zq3_P, 3lnq_A, 2lkx_A, 7q3o_C, 2ld5_A, 6es3_K, 1jgg_B, 5jlw_D, 4xrs_G, 3a01_E, 3rkq_B, 6m3d_C, 5flv_I, 2hdd_A, 1b72_A, 5zjt_E, 4cyc_A, 2r5y_A, 1puf_B, 7psx_B, 2hos_A, 2xsd_C, 1e3o_C, 7xrc_C, 1au7_A, 1le8_A, 1du0_A, 4qtr_D, 1o4x_A, 1k61_B, 5hod_A |
| Binding Motifs: | MA0485.1 rgCmATAAATCwy PH0073.1 rkagGTMATWAAyydk |
| Binding Sites: | MA0485.1.1 MA0485.1.10 MA0485.1.11 MA0485.1.12 MA0485.1.13 MA0485.1.14 MA0485.1.15 MA0485.1.16 MA0485.1.17 MA0485.1.18 MA0485.1.19 MA0485.1.2 MA0485.1.20 MA0485.1.3 MA0485.1.4 MA0485.1.5 MA0485.1.6 MA0485.1.7 MA0485.1.8 MA0485.1.9 |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] Shen W.F, Rozenfeld S, Lawrence H.J, Largman C. The Abd-B-like Hox homeodomain proteins can be subdivided by the ability to form complexes with Pbx1a on a novel DNA target. The Journal of biological chemistry 272:8198-206 (1997). [Pubmed] |
| Related annotations: | PaperBLAST |
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