Transcription Factor

Accessions: T111991_1.02 (CISBP 1.02), P38128 (JASPAR 2024)
Names: SMP1, T111991_1.02;, SMP1_YEAST
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:MADS box
Length: 452
Pfam Domains: 9-59 SRF-type transcription factor (DNA-binding and dimerisation domain)
Sequence:
(in bold interface residues)
1 MGRRKIEIEPIKDDRNRTVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEYSSV 60
61 DMSNLLNVHQNNTDLPHNIIEPSDYGDYVKKPRVVLNERKRRRRRATVLQPASHSGSCTV 120
121 SSQDSSSVQNNGNLSAPLASNDAGNAGVSTPLVHCHGAISRSGSNHSDCARNSADYQMLQ 180
181 GGLNSGGSFHANDYKESVDQQHVANEAIHRNFMNKRIRPDTHLLLSESNHSNYHNFYPSP 240
241 YENLPKPSLPASLVGNIPSFQSQFVQVIPANSNPMGKGFNGTGDSESFEAKQKIHPTVAI 300
301 SNTLEGPAPVQAMVHHLHQLNSNRGKLSGKPYLKLNIPKATNDACQRSPAMYSGTASPKT 360
361 DVQATPNQMLASNMSSPLSRSKFLGFKNNDMDDLYHNGRCGSTYVNNKTFFLKPPIGRPP 420
421 KFPKSPSSSIVVFPSSVASSTLKSTSSTNSPD
Interface Residues: 3, 4, 15, 18, 19, 23, 302, 306
3D-footprint Homologues: 1hbx_A, 7x1n_C, 1n6j_A, 1c7u_A, 1mnm_A, 5z7d_C
Binding Motifs: MA0383.1 tkacctwtAATTawaybwscw
M1299_1.02 TTAATAAA
Publications: Newburger D.E, Bulyk M.L. UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic acids research 37:D77-82 (2009). [Pubmed]
Related annotations: PaperBLAST

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