Transcription Factor

Accessions: T154046_1.02 (CISBP 1.02), Q9FL26 (JASPAR 2024), T22946 (AthalianaCistrome v4_May2016)
Names: T154046_1.02;, WRKY8, Probable WRKY transcription factor 8, WRKY DNA-binding protein 8, WRKY transcription factor 8, WRKY8_ARATH, AT5G46350, T22946;
Organisms: Arabidopsis thaliana
Libraries: CISBP 1.02 1, JASPAR 2024 2, AthalianaCistrome v4_May2016 3
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
3 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: experiment type:PBM, family:WRKY, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq
Length: 326
Pfam Domains: 183-240 WRKY DNA -binding domain
Sequence:
(in bold interface residues)
1 MSHEIKDLNNYHYTSSYNHYNINNQNMINLPYVSGPSAYNANMISSSQVGFDLPSKNLSP 60
61 QGAFELGFELSPSSSDFFNPSLDQENGLYNAYNYNSSQKSHEVVGDGCATIKSEVRVSAS 120
121 PSSSEADHHPGEDSGKIRKKREVRDGGEDDQRSQKVVKTKKKEEKKKEPRVSFMTKTEVD 180
181 HLEDGYRWRKYGQKAVKNSPYPRSYYRCTTQKCNVKKRVERSYQDPTVVITTYESQHNHP 240
241 IPTNRRTAMFSGTTASDYNPSSSPIFSDLIINTPRSFSNDDLFRVPYASVNVNPSYHQQQ 300
301 HGFHQQESEFELLKEMFPSVFFKQEP
Interface Residues: 189, 190, 191, 193, 194, 205
3D-footprint Homologues: 6j4f_F, 6j4g_B, 6ir8_A, 6j4e_B, 7z0u_A
Binding Motifs: M1698_1.02 wrGTCAAmg
MA1094.1 wrGTCAAmg
M0792 raaAAAGTCAACgaw
M0820 wwtcGTTGACTTTTt
MA1094.2 waaAAAGTCAACghww
MA1094.3 aAAAGTCAACg
Binding Sites: MA1094.2.5
MA1094.2.7
MA1094.2.2
MA1094.2.3
MA1094.2.9
MA1094.2.10
MA1094.2.4
MA1094.2.1
MA1094.2.11
MA1094.2.12
MA1094.2.13
MA1094.2.14
MA1094.2.15
MA1094.2.16
MA1094.2.17
MA1094.2.18
MA1094.2.19
MA1094.2.20
MA1094.2.6
MA1094.2.8
MA1094.3.2
MA1094.3.1
MA1094.3.19 / MA1094.3.3
MA1094.3.16 / MA1094.3.4 / MA1094.3.6
MA1094.3.10
MA1094.3.12
MA1094.3.13
MA1094.3.14
MA1094.3.11
MA1094.3.15
MA1094.3.17
MA1094.3.18
MA1094.3.20
MA1094.3.5
MA1094.3.7
MA1094.3.8
MA1094.3.9
Publications: Yu D, Chen C, Chen Z. 2001. Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression. Plant Cell. 13:1527-40. [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.