Transcription Factor

Accessions: P17028 (JASPAR 2024)
Names: Retinoic acid suppression protein A, RSG-A, Zinc finger and SCAN domain-containing protein 3, Zinc finger protein 191, Zinc finger protein 24, Zinc finger protein KOX17, ZNF24_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P17028
Length: 368
Pfam Domains: 47-140 SCAN domain
251-271 C2H2-type zinc finger
251-273 Zinc finger, C2H2 type
251-273 C2H2-type zinc finger
268-290 Zinc-finger double domain
279-301 C2H2-type zinc finger
279-301 Zinc finger, C2H2 type
281-301 C2H2-type zinc finger
294-317 Zinc-finger double domain
306-318 C2H2-type zinc finger
307-329 Zinc finger, C2H2 type
307-329 C2H2-type zinc finger
322-345 Zinc-finger double domain
334-358 C2H2-type zinc finger
335-357 Zinc finger, C2H2 type
335-358 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGY 60
61 QDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENG 120
121 EEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWAS 180
181 WELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLNMGVPQIFKYGETCFPKGRFE 240
241 RKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRV 300
301 HTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAE 360
361 KLLNVVKV
Interface Residues: 261, 262, 263, 264, 265, 267, 268, 270, 271, 272, 274, 279, 289, 290, 291, 292, 293, 296, 297, 300, 317, 318, 319, 320, 321, 322, 323, 324, 325, 345, 346, 347, 348, 349, 351, 352, 355, 356
3D-footprint Homologues: 8cuc_F, 7y3l_A, 7n5w_A, 7w1m_H, 2gli_A, 8ssu_A, 1tf6_A, 5v3j_F, 6blw_A, 5kkq_D, 5ei9_F, 8ssq_A, 7eyi_G, 8h9h_G, 2lt7_A, 2i13_A, 6e94_A, 7ysf_A, 6wmi_A, 2jpa_A, 1ubd_C, 2kmk_A, 1tf3_A, 6jnm_A, 1g2f_F, 5k5l_F, 6ml4_A, 4x9j_A, 6u9q_A, 5yel_A, 1mey_C, 5kl3_A, 1f2i_J, 5yj3_D, 5k5i_A, 5und_A, 4m9v_C, 6a57_A, 3uk3_C, 8gn3_A, 1llm_D, 2wbs_A, 7txc_E, 2drp_D, 7y3m_I
Binding Motifs: MA1124.1 CATTCATTCATTC
Binding Sites: MA1124.1.1
MA1124.1.10 / MA1124.1.7
MA1124.1.11
MA1124.1.12
MA1124.1.13
MA1124.1.14
MA1124.1.15
MA1124.1.16
MA1124.1.17
MA1124.1.18
MA1124.1.19
MA1124.1.2
MA1124.1.20
MA1124.1.3
MA1124.1.4
MA1124.1.5
MA1124.1.6
MA1124.1.8
MA1124.1.9
Publications: Albanèse V, Biguet NF, Kiefer H, Bayard E, Mallet J, Meloni R. Quantitative effects on gene silencing by allelic variation at a tetranucleotide microsatellite. Hum Mol Genet 10:1785-92 (2001). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.