Transcription Factor

Accessions: CEBPD_HUMAN (HOCOMOCO 10), P49716 (JASPAR 2024)
Names: C/EBP delta, CCAAT/enhancer-binding protein delta, CEBPD_HUMAN, Nuclear factor NF-IL6-beta
Organisms: Homo sapiens
Libraries: HOCOMOCO 10 1, JASPAR 2024 2
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P49716
Length: 269
Pfam Domains: 191-242 Basic region leucine zipper
196-247 bZIP transcription factor
Sequence:
(in bold interface residues)
1 MSAALFSLDGPARGAPWPAEPAPFYEPGRAGKPGRGAEPGALGEPGAAAPAMYDDESAID 60
61 FSAYIDSMAAVPTLELCHDELFADLFNSNHKAGGAGPLELLPGGPARPLGPGPAAPRLLK 120
121 REPDWGDGDAPGSLLPAQVAACAQTVVSLAAAGQPTPPTSPEPPRSSPRQTPAPGPAREK 180
181 SAGKRGPDRGSPEYRQRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQL 240
241 TRDLAGLRQFFKQLPSPPFLPAAGTADCR
Interface Residues: 197, 198, 200, 201, 202, 204, 205, 208, 209, 223, 236
3D-footprint Homologues: 1gd2_G, 2wt7_A, 1nwq_C, 6mg1_B, 2dgc_A, 5t01_B, 2c9l_Z, 7yq3_E
Binding Motifs: MA0836.1 rTTrCGCAAy
UN0523.1 rsCGGAwrTTGCGyAAy
CEBPD_HUMAN.H10MO.B|M01050 rrTkryGcAAt
MA0836.2 krTTGCACAAyww
MA0836.3 TTGCACAA
UN0523.2 sCGGAwrTTGCGyAAy
Binding Sites: MA0836.3.1 / MA0836.3.7
MA0836.2.1
MA0836.2.10
MA0836.2.11
MA0836.2.12 / MA0836.2.13
MA0836.2.13 / MA0836.2.14
MA0836.2.14 / MA0836.2.15
MA0836.2.15
MA0836.2.16
MA0836.2.17
MA0836.2.16 / MA0836.2.18
MA0836.2.17 / MA0836.2.19
MA0836.2.2
MA0836.2.20
MA0836.2.3
MA0836.2.4
MA0836.2.3 / MA0836.2.5
MA0836.2.5 / MA0836.2.6
MA0836.2.6 / MA0836.2.7
MA0836.2.7 / MA0836.2.8
MA0836.2.9
MA0836.2.12
MA0836.2.18
MA0836.2.19
MA0836.2.2
MA0836.2.20
MA0836.2.4
MA0836.2.8
MA0836.3.10 / MA0836.3.18 / MA0836.3.19 / MA0836.3.5 / MA0836.3.6 / MA0836.3.9
MA0836.3.11 / MA0836.3.13
MA0836.3.12 / MA0836.3.8
MA0836.3.14
MA0836.3.15
MA0836.3.16
MA0836.3.17
MA0836.3.2
MA0836.3.20 / MA0836.3.4
MA0836.3.3
Publications: Osada S, Yamamoto H, Nishihara T, Imagawa M. DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J Biol Chem 271:3891-6 (1996). [Pubmed]
Related annotations: PaperBLAST

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