Transcription Factor

Accessions: T095241_1.02 (CISBP 1.02), Q810N8 (JASPAR 2024)
Names: Rhox11, T095241_1.02;, Q810N8_MOUSE, Reproductive homeobox 11, Reproductive homeobox on X chromosome 11
Organisms: Mus musculus
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q810N8
Notes: experiment type:PBM, family:Homeodomain
Length: 206
Pfam Domains: 94-147 Homeobox domain
Sequence:
(in bold interface residues)
1 MSRKYFYFDYDYYGMSFCEEEITTEPEEKVAYTSNSGGFADEVTGIPKEGHQSSIGEHSC 60
61 VMPNTQDTGREEPEETSKVAETSEQSLFRIPRKAYRFTPGQLWELQAVFVENQYPDALKR 120
121 KELAGLLNVDEQKIKDWFNNKRAKYRKIQREILGGKNITPTQEELRMKTLVESKKIIIFQ 180
181 EQEGDGLFWEHQNIDTQNSPLSLLFS
Interface Residues: 89, 92, 93, 94, 95, 96, 132, 133, 135, 136, 139, 140, 143, 144, 147, 156
3D-footprint Homologues: 2ld5_A, 7psx_B, 2d5v_B, 6m3d_C, 4j19_B, 2lkx_A, 2r5y_A, 1zq3_P, 4xrs_G, 1mnm_C, 6a8r_A, 5zfz_A, 1le8_B, 1k61_B, 5jlw_D, 2xsd_C, 1e3o_C, 1au7_A, 7q3o_C, 1le8_A, 7xrc_C, 1ig7_A, 1du0_A, 5flv_I, 3l1p_A, 1puf_A, 1jgg_B, 5zjt_E, 3a01_E, 2h1k_B, 5hod_A, 3lnq_A, 1puf_B, 4qtr_D, 3cmy_A, 2hdd_A, 1nk2_P, 1fjl_B, 3rkq_B, 6es3_K, 1b72_A, 3d1n_M, 1o4x_A, 4cyc_A, 2hos_A
Binding Motifs: MA0629.1 / PH0157.1 amkmyGCTGTwAwrsrw
PH0158.1 arkmcGCTGTwAwgsrw
M1046_1.02 wwwwACAbcr
MA0629.2 yGCTGTwAw
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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