Transcription Factor

						

			
Accessions: BACH1_TF2 (HumanTF2 1.0)

			
Names: BACH1, BACH1_HUMAN, BTB and CNC homolog 1, HA2303, Transcription regulator protein BACH1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Uniprot: O14867
Notes: Ensembl ID: ENSG00000156273; Construct type: TF2(3xFLAG); TF family: bZIP; Clone source: MGC
Length: 144
Pfam Domains:    38-119 bZIP Maf transcription factor
   70-118 bZIP transcription factor
   71-111 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 CPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISLSRNDFQSLLKMHKLT   60
  61 PEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQSEKESLLKERDHILSTLG  120
 121 ETKQNLTGLCQKVCKEAALSQEQI
Interface Residues: 72, 75, 76, 77, 79, 80, 83, 84, 87
3D-footprint Homologues: 2wt7_B, 7x5e_E, 1gd2_G, 4eot_A, 7x5e_F, 1skn_P, 2wt7_A, 5vpe_D, 5t01_B
Binding Motifs: BACH1 ATGACTCAt
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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