Transcription Factor
| Accessions: | T028098_1.02 (CISBP 1.02), UP00473A (UniPROBE 20160601), P38749 (JASPAR 2024) |
| Names: | T028098_1.02;, YAP3, Yeast AP-1, YAP3_YEAST |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, UniPROBE 20160601 2, JASPAR 2024 3 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Description: | Yeast AP-1: Basic leucine zipper (bZIP) transcription factor |
| Notes: | experiment type:PBM, family:bZIP |
| Length: | 330 |
| Pfam Domains: | 144-204 bZIP transcription factor |
| Sequence: (in bold interface residues) | 1 MTPSNMDDNTSGFMKFINPQCQEEDCCIRNSLFQEDSKCIKQQPDLLSEQTAPFPILEDQ 60 61 CPALNLDRSNNDLLLQNNISFPKGSDLQAIQLTPISGDYSTYVMADNNNNDNDSYSNTNY 120 121 FSKNNGISPSSRSPSVAHNENVPDDSKAKKKAQNRAAQKAFRERKEARMKELQDKLLESE 180 181 RNRQSLLKEIEELRKANTEINAENRLLLRSGNENFSKDIEDDTNYKYSFPTKDEFFTSMV 240 241 LESKLNHKGKYSLKDNEIMKRNTQYTDEAGRHVLTVPATWEYLYKLSEERDFDVTYVMSK 300 301 LQGQECCHTHGPAYPRSLIDFLVEEATLNE |
| Interface Residues: | 150, 153, 154, 155, 157, 158, 161, 162, 250, 314, 317, 318, 319 |
| 3D-footprint Homologues: | 1gd2_G, 2dgc_A, 2ih2_D |
| Binding Motifs: | M0354_1.02 maTTACkwAa UP00473A_1 / UP00473A_2 gsmmamtATTACGTAAtgsmryc UP00473A_3 ATTAcTAAT MA0416.1 aTTACGTa MA0416.2 aTTACGT |
| Binding Sites: | CTGACTAA ACGTAATA ACGTAATC ATATTAAA ATATTATG ATGACTAA ATTAATAA ATTACGTA ATTACTAA ATTAGTAA ATTAGTCA CTTACTAA CTTAGTAA TTACATAA TTACGTAA TTACTAAA TTATATAA ATATTACG ATTACGTG ATTATTAA |
| Publications: | Gordân R, Murphy KF, McCord RP, Zhu C, Vedenko A, Bulyk ML. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol : (2011). [Pubmed] Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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