Transcription Factor
| Accessions: | Q14186 (JASPAR 2024) |
| Names: | DRTF1-polypeptide 1, E2F dimerization partner 1, TFDP1_HUMAN, Transcription factor Dp-1 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 410 |
| Pfam Domains: | 111-193 E2F/DP family winged-helix DNA-binding domain 200-342 Transcription factor DP |
| Sequence: (in bold interface residues) | 1 MAKDAGLIEANGELKVFIDQNLSPGKGVVSLVAVHPSTVNPLGKQLLPKTFGQSNVNIAQ 60 61 QVVIGTPQRPAASNTLVVGSPHTPSTHFASQNQPSDSSPWSAGKRNRKGEKNGKGLRHFS 120 121 MKVCEKVQRKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMN 180 181 IISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRN 240 241 RHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVL 300 301 KRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVFITTAGSTSNGTRFS 360 361 ASDLTNGADGMLATSSNGSQYSGSRVETPVSYVGEDDEEDDDFNENDEDD |
| Interface Residues: | 164, 165, 166, 167, 168, 170, 209 |
| 3D-footprint Homologues: | 1cf7_B, 4yo2_A, 1cf7_A, 2dgc_A |
| Binding Motifs: | MA1122.1 gsGCGGGAAss MA1122.2 sGCGGGAA |
| Binding Sites: | MA1122.2.14 MA1122.2.19 / MA1122.2.2 / MA1122.2.3 / MA1122.2.6 / MA1122.2.8 / MA1122.2.9 MA1122.1.1 MA1122.1.10 / MA1122.1.11 MA1122.1.12 MA1122.1.13 MA1122.1.14 MA1122.1.15 MA1122.1.16 MA1122.1.17 MA1122.1.18 MA1122.1.19 MA1122.1.2 MA1122.1.20 MA1122.1.3 MA1122.1.4 MA1122.1.5 MA1122.1.6 MA1122.1.7 MA1122.1.8 MA1122.1.9 MA1122.2.20 MA1122.2.1 MA1122.2.10 / MA1122.2.11 MA1122.2.12 MA1122.2.13 / MA1122.2.5 / MA1122.2.7 MA1122.2.15 / MA1122.2.17 MA1122.2.16 MA1122.2.18 MA1122.2.4 |
| Publications: | Zhang Y, Venkatraj VS, Fischer SG, Warburton D, Chellappan SP. Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family. Genomics 39:95-8 (1997). [Pubmed] |
| Related annotations: | PaperBLAST |
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