Transcription Factor

Accessions: 6gat_A (3D-footprint 20231221), 7gat_A (3D-footprint 20231221)
Names: AREA_EMENI, NITROGEN REGULATORY PROTEIN AREA
Organisms: Emericella nidulans, Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P17429
Length: 66
Pfam Domains: 12-45 GATA zinc finger
Sequence:
(in bold interface residues)
1 MKNGEQNGPTTCTNCFTQTTPVWRRNPEGQPLCNACGLFLKLHGVVRPLSLKTDVIKKRN 60
61 RNSANS
Interface Residues: 21, 22, 24, 34, 38, 39, 42, 59, 61
3D-footprint Homologues: 1gat_A, 3dfx_B, 4gat_A, 3vd6_C
Binding Motifs: 6gat_A TGATnG
7gat_A TGat
Binding Sites: 6gat_B / 7gat_B
6gat_C / 7gat_C
Publications: Starich M.R, Wikström M, Schumacher S, Arst H.N, Gronenborn A.M, Clore G.M. The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity. Journal of molecular biology 277:621-34 (1998). [Pubmed]
Related annotations: PaperBLAST

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