Transcription Factor

						

			
Accessions: Q05BX2 (JASPAR 2024)

			
Names: MEF2D protein, Myocyte-specific enhancer factor 2D, Q05BX2_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q05BX2
Length: 139
Pfam Domains:     10-59 SRF-type transcription factor (DNA-binding and dimerisation domain)
Sequence: 
(in bold interface residues)		   1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST   60
  61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA  120
 121 SEELDGLFRRYGGPCWGVT
Interface Residues: 3, 4, 15, 18, 19, 23
3D-footprint Homologues: 1hbx_A, 1n6j_A, 1c7u_A, 7x1n_C, 1mnm_A
Binding Motifs: MA0773.1 dCTAwAAATAGm
			
Publications: Wales S, Hashemi S, Blais A, McDermott JC. Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling. Nucleic Acids Res 42:11349-62 (2014). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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