Transcription Factor
Accessions: | BHLHB2_DBD (HumanTF 1.0) |
Names: | BHE40_HUMAN, BHLHB2, bHLHe40, Class B basic helix-loop-helix protein 2, Class E basic helix-loop-helix protein 40, DEC1, Differentially expressed in chondrocytes protein 1, Enhancer-of-split and hairy-related protein 2, SHARP-2, Stimulated by retinoic acid gene 13 protein |
Organisms: | Homo sapiens |
Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
Uniprot: | O14503 |
Notes: | Ensembl ID: ENSG00000134107; DNA-binding domain sequence; TF family: bHLH; Clone source: Megaman |
Length: | 114 |
Pfam Domains: | 28-78 Helix-loop-helix DNA-binding domain |
Sequence: (in bold interface residues) | 1 PAHMYQVYKSRRGIKRSEDSKETYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLG 60 61 HLEKAVVLELTLKHVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFC |
Interface Residues: | 27, 28, 29, 31, 32, 35, 36, 62 |
3D-footprint Homologues: | 1an4_A, 7d8t_A, 5v0l_A, 4h10_A, 7f2f_B, 5eyo_A, 1a0a_B, 7xi3_A, 7rcu_E, 1am9_A, 6g1l_A, 4zpk_A, 7ssa_L, 5nj8_D, 8osl_P, 8osl_O, 7xhv_B, 4h10_B, 5nj8_C, 7xi3_B, 4zpr_B, 5v0l_B |
Binding Motifs: | BHLHB2_DBD vkCACGTGmc |
Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.