Transcription Factor

						

			
Accessions: P62515 (JASPAR 2024)

			
Names: Brain-4, Brain-specific homeobox/POU domain protein 4, Brn-4, Oct-9, Octamer-binding protein 9, Octamer-binding transcription factor 9, OTF-9, PO3F4_MOUSE, POU domain, class 3, transcription factor 4
Organisms: Mus musculus, Rattus norvegicus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 361
Pfam Domains:   187-260 Pou domain - N-terminal to homeobox domain
  279-335 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MATAASNPYSILSSSSLVHADSAGMQQGSPFRNPQKLLQSDYLQGVPSNGHPLGHHWVTS   60
  61 LSDGGPWSSTLATSPLDQQDVKPGREDLQLGAIIHHRSPHVAHHSPHTNHPNAWGASPAP  120
 121 NSSITSSGQPLNVYSQPGFTVSGMLEHGGLTPPPAAASTQSLHPVLREPPDHGELGSHHC  180
 181 QDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQL  240
 241 SFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKC  300
 301 PKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQPHEVYSHTVKTDASCHD  360
 361 L
Interface Residues: 212, 228, 229, 230, 231, 233, 234, 240, 244, 277, 279, 280, 281, 282, 320, 321, 323, 324, 327, 328, 331, 332, 335
3D-footprint Homologues: 3d1n_M, 3l1p_A, 7u0g_M, 8g87_X, 2xsd_C, 1e3o_C, 1au7_A, 1o4x_A, 7xrc_C, 3lnq_A, 1puf_A, 1ig7_A, 6a8r_A, 1fjl_B, 3cmy_A, 2h1k_B, 5zfz_A, 1jgg_B, 1nk2_P, 1zq3_P, 2lkx_A, 2r5y_A, 1puf_B, 5hod_A, 3a01_E, 4xrs_G, 3rkq_B, 2ld5_A, 5jlw_D, 7q3o_C, 1le8_A, 7psx_B, 5flv_I, 2hdd_A, 1mnm_C, 1du0_A, 5zjt_E, 4cyc_A, 4qtr_D, 1k61_B, 6es3_K, 1b72_A
Binding Motifs: PH0149.1 rmttAATTAATTAadtc
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.