Transcription Factor
| Accessions: | Q04744 (JASPAR 2024) |
| Names: | Empty spiracles homolog 2, Empty spiracles-like protein 2, EMX2_MOUSE, Homeobox protein EMX2 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q04744 |
| Length: | 253 |
| Pfam Domains: | 156-212 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAA 60 61 GRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTF 120 121 YPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYV 180 181 VGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATK 240 241 QASPEEIDVTSDD |
| Interface Residues: | 153, 156, 157, 158, 159, 197, 198, 200, 201, 204, 205, 208, 209, 212 |
| 3D-footprint Homologues: | 1ig7_A, 6a8r_A, 3d1n_M, 1fjl_B, 5zfz_A, 2h1k_B, 1puf_A, 3cmy_A, 1nk2_P, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 7q3o_C, 6es3_K, 2ld5_A, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 2hos_A, 5jlw_D, 4cyc_A, 1b72_A, 4xrs_G, 3a01_E, 5flv_I, 5zjt_E, 1e3o_C, 1au7_A, 2xsd_C, 1le8_A, 7xrc_C, 4j19_B, 1mnm_C, 1puf_B, 1k61_B, 4xrm_B, 3l1p_A, 1o4x_A, 1le8_B, 1du0_A, 8g87_X, 4qtr_D |
| Binding Motifs: | PH0027.1 wvmrCTAATTAGykshy |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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